000151274 001__ 151274
000151274 005__ 20250307114714.0
000151274 0247_ $$2doi$$a10.3390/brainsci11030348
000151274 0248_ $$2sideral$$a124317
000151274 037__ $$aART-2021-124317
000151274 041__ $$aeng
000151274 100__ $$aBaliyan, S.
000151274 245__ $$aDifferential Susceptibility to the Impact of the COVID-19 Pandemic on Working Memory, Empathy, and Perceived Stress: The Role of Cortisol and Resilience
000151274 260__ $$c2021
000151274 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151274 5203_ $$aThere are important individual differences in adaptation and reactivity to stressful challenges. Being subjected to strict social confinement is a distressful psychological experience leading to reduced emotional well-being, but it is not known how it can affect the cognitive and empathic tendencies of different individuals. Cortisol, a key glucocorticoid in humans, is a strong modulator of brain function, behavior, and cognition, and the diurnal cortisol rhythm has been postulated to interact with environmental stressors to predict stress adaptation. The present study investigates in 45 young adults (21.09 years old, SD = 6.42) whether pre-pandemic diurnal cortisol indices, overall diurnal cortisol secretion (AUCg) and cortisol awakening response (CAR) can predict individuals’ differential susceptibility to the impact of strict social confinement during the Coronavirus Disease 2019 (COVID-19) pandemic on working memory, empathy, and perceived stress. We observed that, following long-term home confinement, there was an increase in subjects’ perceived stress and cognitive empathy scores, as well as an improvement in visuospatial working memory. Moreover, during confinement, resilient coping moderated the relationship between perceived stress scores and pre-pandemic AUCg and CAR. In addition, in mediation models, we observed a direct effect of AUCg and an indirect effect of both CAR and AUCg, on change in perceived self-efficacy. These effects were parallelly mediated by the increase in working memory span and cognitive empathy. In summary, our findings reveal the role of the diurnal pattern of cortisol in predicting the emotional impact of the COVID-19 pandemic, highlighting a potential biomarker for the identification of at-risk groups following public health crises.
000151274 536__ $$9info:eu-repo/grantAgreement/ES/MCIU/RTI2018-094627-B-I00$$9info:eu-repo/grantAgreement/ES/MICIU/PGC2018-101680-B-I00
000151274 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000151274 590__ $$a3.333$$b2021
000151274 591__ $$aNEUROSCIENCES$$b176 / 275 = 0.64$$c2021$$dQ3$$eT2
000151274 592__ $$a0.727$$b2021
000151274 593__ $$aNeuroscience (miscellaneous)$$c2021$$dQ3
000151274 594__ $$a3.1$$b2021
000151274 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151274 700__ $$aCimadevilla, J.M.
000151274 700__ $$ade Vidania, S.
000151274 700__ $$0(orcid)0000-0002-7048-3795$$aPulopulos, M.M.$$uUniversidad de Zaragoza
000151274 700__ $$aSandi, C.
000151274 700__ $$aVenero, C.
000151274 7102_ $$14009$$2725$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicobiología
000151274 773__ $$g11, 3 (2021), 348 [21 pp.]$$pBrain sci.$$tBrain Sciences$$x2076-3425
000151274 8564_ $$s3583959$$uhttps://zaguan.unizar.es/record/151274/files/texto_completo.pdf$$yVersión publicada
000151274 8564_ $$s2807020$$uhttps://zaguan.unizar.es/record/151274/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151274 909CO $$ooai:zaguan.unizar.es:151274$$particulos$$pdriver
000151274 951__ $$a2025-03-07-09:31:06
000151274 980__ $$aARTICLE