000151284 001__ 151284
000151284 005__ 20251017144611.0
000151284 0247_ $$2doi$$a10.1016/j.recot.2020.09.006
000151284 0248_ $$2sideral$$a124142
000151284 037__ $$aART-2021-124142
000151284 041__ $$aspa
000151284 100__ $$aUrgel Granados, A.C.
000151284 245__ $$aInfluencia del ácido tranexámico intraarticular sobre el ahorro de costes y los resultados funcionales precoces en artroplastia total de rodilla
000151284 260__ $$c2021
000151284 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151284 5203_ $$aBackground and aim: Total knee arthroplasty (TKA) is a frequent intervention that can associate significant blood loss. There are several methods to avoid transfusions. One of the most relevant is tranexamic acid (TXA). Our purpose is to analyse the efficacy in terms of blood savings, transfusion needs, functional results, and cost-effectiveness of intra-articular (IA) administration in TKA. Materials and methods: We conducted a retrospective analysis of historical cohorts (75 patients each) between January 2015 and December 2016. We included 150 patients (59.3% women) with a mean age of 73.58 years. The intervention consisted of administering 2 g of IA TXA with a contact time of 30 minutes. Demographic data, preoperative haematological status, surgery data, estimated total blood loss (ETBL), need for transfusion, functional results, and cost analysis were collected. The level of statistical significance was p = 0, 05. Results: The incidence of transfusion was 17.33% in the control group and 5.33% in the TXA group (p = 0.039), with a relative risk reduction of 78.3%. The TXA cohort showed a reduction in ETBL (p < 0.0005), units transfused (p = 0.019) and length of stay (p = 0.004). All early functional parameters also improved, including a 10° improvement in both flexion and extension (p < 0.0005). The use of IA TXA resulted in savings of 337.78 € per patient. Conclusions: In our experience, the administration of IA TXA in TKA is a cost-effective and efficient measure in terms of blood savings and immediate postoperative functional improvement.
000151284 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000151284 592__ $$a0.2$$b2021
000151284 593__ $$aSurgery$$c2021$$dQ3
000151284 593__ $$aOrthopedics and Sports Medicine$$c2021$$dQ3
000151284 594__ $$a1.0$$b2021
000151284 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151284 700__ $$0(orcid)0000-0001-5067-6488$$aTorres Campos, A.$$uUniversidad de Zaragoza
000151284 700__ $$aRoyo Agustín, M.
000151284 700__ $$aRillo Lázaro, A.
000151284 700__ $$aEspallargas Donate, M.T.
000151284 700__ $$aCastro Sauras, Á.
000151284 7102_ $$11013$$2830$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Traumatología y Ortopedia
000151284 773__ $$g65, 4 (2021), 285-293$$pRev. esp. cir. ortop. traumatol.$$tRevista Espanola de Cirugia Ortopedica y Traumatologia$$x1888-4415
000151284 8564_ $$s869736$$uhttps://zaguan.unizar.es/record/151284/files/texto_completo.pdf$$yVersión publicada
000151284 8564_ $$s1998518$$uhttps://zaguan.unizar.es/record/151284/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151284 909CO $$ooai:zaguan.unizar.es:151284$$particulos$$pdriver
000151284 951__ $$a2025-10-17-14:17:24
000151284 980__ $$aARTICLE