000151554 001__ 151554 000151554 005__ 20251017144652.0 000151554 0247_ $$2doi$$a10.3390/life15020261 000151554 0248_ $$2sideral$$a143187 000151554 037__ $$aART-2025-143187 000151554 041__ $$aeng 000151554 100__ $$0(orcid)0000-0002-5621-1937$$aSánchez-Cano, Ana$$uUniversidad de Zaragoza 000151554 245__ $$aColorimetric and Photobiological Properties of Light Transmitted Through Low-Vision Filters: Simulated Potential Impact on ipRGCs Responses Considering Crystalline Lens Aging 000151554 260__ $$c2025 000151554 5060_ $$aAccess copy available to the general public$$fUnrestricted 000151554 5203_ $$aThis study aims to investigate the potential impact of commercial low-vision filters on intrinsically photosensitive retinal ganglion cells (ipRGCs), which have significantly advanced our understanding of non-image-forming visual functions. A comprehensive analysis by modeling the potential responses of ipRGCs to commercially available low-vision filters was conducted, focusing on how the spectral properties of these filters could alter ipRGC function. Additionally, the influence of aging on the crystalline lens was considered. Colorimetric changes in the transmitted light by these filters were also analyzed, highlighting variations based on the manufacturer. The study uncovered the diverse responses of ipRGCs to fifty low-vision filters, shedding light on the potential modifications in ipRGC stimulation and visual function. Notably, the consideration of aging in the crystalline lens revealed significant alterations in ipRGC response. Furthermore, the analysis of colorimetric changes demonstrated substantial differences in the light transmitted by these filters, with variations dependent on the manufacturer. This research underscores the nuanced relationship between low-vision filters and ipRGCs, providing insights into their potential impact on visual function. The varying responses observed, coupled with the influence of aging on the crystalline lens, emphasize the complexity of this interaction. Additionally, the distinct colorimetric changes based on filter manufacturer suggest the need for tailored approaches in enhancing visual perception for individuals with visual impairments. 000151554 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es 000151554 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000151554 700__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza 000151554 700__ $$0(orcid)0000-0003-2968-228X$$aAporta, Justiniano 000151554 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica 000151554 773__ $$g15, 2 (2025), 261 [17 pp.]$$pLife (Basel)$$tLife$$x2075-1729 000151554 8564_ $$s2670086$$uhttps://zaguan.unizar.es/record/151554/files/texto_completo.pdf$$yVersión publicada 000151554 8564_ $$s2620023$$uhttps://zaguan.unizar.es/record/151554/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000151554 909CO $$ooai:zaguan.unizar.es:151554$$particulos$$pdriver 000151554 951__ $$a2025-10-17-14:36:47 000151554 980__ $$aARTICLE