000151647 001__ 151647
000151647 005__ 20250319155217.0
000151647 0247_ $$2doi$$a10.1039/d0cb00218f
000151647 0248_ $$2sideral$$a126650
000151647 037__ $$aART-2021-126650
000151647 041__ $$aeng
000151647 100__ $$aBieganski P.
000151647 245__ $$aBrief survey on organometalated antibacterial drugs and metal-based materials with antibacterial activity
000151647 260__ $$c2021
000151647 5060_ $$aAccess copy available to the general public$$fUnrestricted
000151647 5203_ $$aRising bacterial antibiotic resistance is a global threat. To deal with it, new antibacterial agents and antiseptic materials need to be developed. One alternative in this quest is the organometallic derivatization of well-established antibacterial drugs and also the fabrication of advanced metal-based materials having antibacterial properties. Metal-based agents and materials often show new modes of antimicrobial action which enable them to overcome drug resistance in pathogenic bacterial strains. This review summarizes recent (2017-2020) progress in the field of organometallic-derived antibacterial drugs and metal-based materials having antibacterial activity. Specifically, it covers organometallic derivatives of antibacterial drugs including ß-lactams, ciprofloxacin, isoniazid, trimethoprim, sulfadoxine, sulfamethoxazole, and ethambutol as well as non-antibacterial drugs like metformin, phenformin and aspirin. Recent advances and reported clinical trials in the use of metal-based nanomaterials as antibiofouling coatings on medical devices, as photocatalytic agents in indoor air pollutant control, and also as photodynamic/photothermal antimicrobial agents are also summarized.
000151647 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000151647 592__ $$a0.847$$b2021
000151647 593__ $$aBiochemistry$$c2021$$dQ1
000151647 593__ $$aMolecular Biology$$c2021$$dQ1
000151647 593__ $$aChemistry (miscellaneous)$$c2021$$dQ1
000151647 594__ $$a1.7$$b2021
000151647 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000151647 700__ $$aSzczupak L.
000151647 700__ $$0(orcid)0000-0003-3165-0156$$aArruebo M.$$uUniversidad de Zaragoza
000151647 700__ $$aKowalski K.
000151647 7102_ $$15005$$2555$$aUniversidad de Zaragoza$$bDpto. Ing.Quím.Tecnol.Med.Amb.$$cÁrea Ingeniería Química
000151647 773__ $$g2, 2 (2021), 368-386$$pRSC chem. biol.$$tRSC chemical biology$$x2633-0679
000151647 8564_ $$s6842972$$uhttps://zaguan.unizar.es/record/151647/files/texto_completo.pdf$$yVersión publicada
000151647 8564_ $$s2357372$$uhttps://zaguan.unizar.es/record/151647/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000151647 909CO $$ooai:zaguan.unizar.es:151647$$particulos$$pdriver
000151647 951__ $$a2025-03-19-14:19:59
000151647 980__ $$aARTICLE