000152019 001__ 152019
000152019 005__ 20250326144154.0
000152019 0247_ $$2doi$$a10.1007/s10856-025-06870-x
000152019 0248_ $$2sideral$$a143395
000152019 037__ $$aART-2025-143395
000152019 041__ $$aeng
000152019 100__ $$aCordero García-Galán, Enrique
000152019 245__ $$aElectromagnetic induction disinfection applied to cemented knee arthroplasty implants: safety evaluation of potential changes in the bone cement
000152019 260__ $$c2025
000152019 5060_ $$aAccess copy available to the general public$$fUnrestricted
000152019 5203_ $$aBackground: Electromagnetic induction heating is a newly developed disinfection method aimed at improving periprosthetic infection outcomes after Debridement and Implant Retention (DAIR). One safety concern is its effect over polymethylmethacrylate(PMMA). The objective of this in-vitro study is to assess such effect on cement adjacent to metallic arthroplasty components. Methods: Two different PMMA products, with and without antibiotic, were applied on three total-knee arthroplasty implants. A portable device was used to administer induction-heating protocols: 70 °C, 3.5 min and 100 °C, 3.5 min, while the third prosthesis served as control. The 602 cm−1 and 558 cm−1 bands in Raman spectroscopy were used to assess isotactic and syndiotactic components of PMMA, while 1339 cm−1, 1295 cm−1 and 882 cm−1 bands in infrared spectroscopy (ATR-FTIR) were used to assess crystallinity. Results: Isotactic/syndiotactic ratios were 0.27(±0.02) for antibiotic-free cement, and 0.41(±0.02) for gentamicin-loaded cement. After induction-heating protocols, isotactic fraction increased in antibiotic-free cement, and decreased in gentamicin-loaded cement. No evidence of crystallization was found in ATR-FTIR, except for a small increase in 1340 cm−1 band after 100 °C protocol. Conclusions: Spectroscopic techniques confirmed that PMMA only experienced minor structural changes after induction heating treatments. From a structural viewpoint, these results suggest that electromagnetic induction heating could be a safe disinfection technique for cemented implants in total knee arthroplasty
000152019 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000152019 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000152019 700__ $$0(orcid)0000-0001-9972-0902$$aMedel Rezusta, Francisco Javier$$uUniversidad de Zaragoza
000152019 700__ $$0(orcid)0000-0001-8399-4650$$aSarnago, Héctor$$uUniversidad de Zaragoza
000152019 700__ $$0(orcid)0000-0002-9655-5531$$aBurdio, José M.$$uUniversidad de Zaragoza
000152019 700__ $$0(orcid)0000-0002-1284-9007$$aLucía, Óscar$$uUniversidad de Zaragoza
000152019 700__ $$aEsteban, Jaime
000152019 700__ $$aGómez-Barrena, Enrique
000152019 7102_ $$15008$$2785$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Tecnología Electrónica
000152019 7102_ $$15004$$2545$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Ingeniería Mecánica
000152019 773__ $$g36, 1 (2025), 25 pp.$$pJ. mater. sci., Mater. med. (Dordr., Online)$$tJournal of Materials Science: Materials in Medicine$$x1573-4838
000152019 8564_ $$s6061249$$uhttps://zaguan.unizar.es/record/152019/files/texto_completo.pdf$$yVersión publicada
000152019 8564_ $$s2094389$$uhttps://zaguan.unizar.es/record/152019/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000152019 909CO $$ooai:zaguan.unizar.es:152019$$particulos$$pdriver
000152019 951__ $$a2025-03-26-13:53:22
000152019 980__ $$aARTICLE