000152053 001__ 152053
000152053 005__ 20250326144155.0
000152053 0247_ $$2doi$$a10.1111/ijpo.12817
000152053 0248_ $$2sideral$$a126843
000152053 037__ $$aART-2021-126843
000152053 041__ $$aeng
000152053 100__ $$0(orcid)0000-0003-2005-8229$$aGonzález-Gil E.M.$$uUniversidad de Zaragoza
000152053 245__ $$aImpaired metabolic health over-time and high abdominal fat are prospectively associated with high-sensitivity C-reactive protein in children: The IDEFICS study
000152053 260__ $$c2021
000152053 5060_ $$aAccess copy available to the general public$$fUnrestricted
000152053 5203_ $$aBackground: Metabolic risk and inflammatory state have an early life onset and are associated with future diseases. Objectives: To assess the association between metabolic syndrome (MetS) and metabolic health with high-sensitive C-reactive protein (hsCRP), cross-sectionally and longitudinally, in children. Methods: 2913 European children (2-10 years) from eight countries from the IDEFICS study were investigated. Data were collected at baseline and 2 years later (follow-up). A MetS z-score was computed with waist circumference (WC), insulin resistance index, blood pressure, high-density lipoprotein cholesterol and triglycerides. Metabolically unhealthy (MU) status was assessed. Multi-level linear and logistic regressions were performed. Results: Among the MetS markers, WC was more consistently associated with hsCRP cross-sectional and prospectively. Baseline MetS score was significantly associated with greater risk of high hsCRP at follow-up and with prevalence and incidence of hsCRP. Those children who became MU overtime were significantly (P <.05) associated with future higher levels of hsCRP, independently of weight status at baseline. Conclusions: Transition over time to a MU state was associated with higher levels of hsCRP at follow-up, independent of weight status at baseline. Screening of metabolic factors and routine measurement of WC are needed to prevent inflammatory status and related chronic diseases in children.
000152053 536__ $$9info:eu-repo/grantAgreement/EUR/FP6/FOOD-016181
000152053 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000152053 590__ $$a3.91$$b2021
000152053 591__ $$aPEDIATRICS$$b27 / 130 = 0.208$$c2021$$dQ1$$eT1
000152053 592__ $$a1.2$$b2021
000152053 593__ $$aHealth Policy$$c2021$$dQ1
000152053 593__ $$aPublic Health, Environmental and Occupational Health$$c2021$$dQ1
000152053 593__ $$aNutrition and Dietetics$$c2021$$dQ1
000152053 594__ $$a6.6$$b2021
000152053 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000152053 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno L.A.$$uUniversidad de Zaragoza
000152053 700__ $$aNappo A.
000152053 700__ $$0(orcid)0000-0002-7297-6104$$aSantabárbara J.$$uUniversidad de Zaragoza
000152053 700__ $$aWolters M.
000152053 700__ $$aRusso P.
000152053 700__ $$aDe Henauw S.
000152053 700__ $$aVeidebaum T.
000152053 700__ $$aMolnar D.
000152053 700__ $$aHunsberger M.
000152053 700__ $$aFraterman A.
000152053 700__ $$aIacoviello L.
000152053 700__ $$aTornaritis M.
000152053 700__ $$aAhrens W.
000152053 700__ $$aBel-Serrat S.
000152053 700__ $$aon behalf the IDEFICS consortium
000152053 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000152053 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000152053 773__ $$g16, 11 (2021), e12817 [9 pp.]$$pPediatr. obes.$$tPediatric obesity$$x2047-6302
000152053 8564_ $$s856604$$uhttps://zaguan.unizar.es/record/152053/files/texto_completo.pdf$$yVersión publicada
000152053 8564_ $$s1936589$$uhttps://zaguan.unizar.es/record/152053/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000152053 909CO $$ooai:zaguan.unizar.es:152053$$particulos$$pdriver
000152053 951__ $$a2025-03-26-13:54:07
000152053 980__ $$aARTICLE