@article{Guyon:152891,
author = "Guyon, Maya and Maria Teresa Verde Arribas",
title = "{Dermatitis atópica canina: Respuesta al tratamiento con
oclacitinib y/o lokivetmab en función del fenotipo
clínico y la raza.}",
year = "2024",
note = "Atopic dermatitis is a chronic skin syndrome: the close
relationship between genetic, environmental and immune
factors conditions the integrity of the skin barrier in
patients. The treatment of atopic dermatitis is complex in
both humans and dogs. The following development will be
based on the current scientific literature to support the
hypothesis of the possible existence of a racial
predisposition in the response to treatment with
oclacitinib and lokivetmab and would be an interesting
topic to develop in studies of larger numbers of patients.
In the first part, the pathogenesis of atopic dermatitis
will be recalled and the mechanisms of action of the two
drugs studied will be explained. In the following part, the
main differences with human atopic dermatitis and the
different existing treatments in human medicine will be
studied, in order to know if there are different treatments
according to the type of skin affected (i.e. according to
the ethnicity to which the patient belongs). Finally, a
statistical study will be carried out with patients from
the Dermatology Service of the Veterinary Hospital of the
University of Zaragoza (Dermatology-HCV-UNIZAR) treated
with oclacitinib and/or lokivetmab, in five different
breeds of dogs (Shih Tzu, Water dog, Bichon, French
Bulldog, Yorkshire Terrier), to see if the variability in
the results obtained with each treatment and the breed of
dog can be correlated.",
}