doi:10.70462/cells.2025.1.001engDoweidar, Mohamed H.Embracing cellular complexity: Toward integrative, mechanobiological, and computational frontiers in cell scienceART-2025-143854In recent decades, cell biology has evolved from a discipline centered on isolated structures and pathways into a vibrant, multidisciplinary science that seeks to understand the cell as a dynamic, complex system. This transformation has been fueled by progress in imaging, high-throughput omics, biomechanical measurements, and - critically - advanced computational modeling. These developments now allow us to probe, quantify, and simulate cell behavior across biological, temporal, and mechanical scales.2025http://zaguan.unizar.es/record/15659210.70462/cells.2025.1.001http://zaguan.unizar.es/record/156592oai:zaguan.unizar.es:156592info:eu-repo/grantAgreement/ES/DGA/T24-23Rinfo:eu-repo/grantAgreement/ES/MICINN/PID2022-138572OB-C44Advances in Cells 1, 1 (2025), [1 pp.]byhttps://creativecommons.org/licenses/by/4.0/deed.esinfo:eu-repo/semantics/openAccess