000156610 001__ 156610 000156610 005__ 20251017144634.0 000156610 0247_ $$2doi$$a10.1016/j.sleep.2025.106527 000156610 0248_ $$2sideral$$a143894 000156610 037__ $$aART-2025-143894 000156610 041__ $$aeng 000156610 100__ $$aZareba, Michal Rafal 000156610 245__ $$aSubjective sleep quality in healthy young adults moderates associations of sensitivity to punishment and reward with functional connectivity of regions relevant for insomnia disorder 000156610 260__ $$c2025 000156610 5060_ $$aAccess copy available to the general public$$fUnrestricted 000156610 5203_ $$aChronic unhealthy sleeping behaviours are a major risk factor for the emergence of mood and anxiety disorders. Nevertheless, we are still lacking understanding why some individuals are more prone than others to affective dysregulation caused by sleep disruption. With preliminary evidence suggesting that brain activity during positive and negative emotional processing might play an important modulating role, we conducted whole-brain resting-state functional connectivity analyses in a large cohort of healthy young adults (N = 155). Using regions consistently affected in insomnia disorder as seeds, we investigated sleep quality-related neural connectivity patterns that were both insensitive and sensitive to the interactions with individual measures of reward and punishment processing, additionally assessing the links with indices of emotional health. The majority of the findings reflected interactions between sleep quality and reinforcement sensitivity, with the opposite associations reported in the good and poor sleepers. One of such connections, the coupling between precentral gyrus and posterior insula, was additionally negatively linked to trait anxiety, with the lowest connectivity values observed in poor sleepers with higher sensitivity to punishment. In turn, the only finding associated solely with sleep quality, i.e. coupling between subgenual anterior cingulate cortex and thalamus, was also related to the habitual use of emotion suppression strategies. As such, the present study provides evidence that reinforcement sensitivity plays an essential role in understanding the associations of poor sleep quality with brain connectivity and emotional health, hinting at a potential link that may help explain individual differences in susceptibility to sleep-related affective dysregulation 000156610 536__ $$9info:eu-repo/grantAgreement/ES/MCIN/RYC2021-033809-I$$9info:eu-repo/grantAgreement/ES/MICINN-AEI/PID2021-127516NB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/PID2019-105077RJ-I00$$9info:eu-repo/grantAgreement/ES/MICIU/RYC2019-028370-I 000156610 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es 000156610 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000156610 700__ $$aDavydova, Tatiana 000156610 700__ $$aPalomar-García, María-Ángeles$$uUniversidad de Zaragoza 000156610 700__ $$0(orcid)0000-0002-0912-5139$$aAdrián-Ventura, Jesús$$uUniversidad de Zaragoza 000156610 700__ $$aCostumero, Victor 000156610 700__ $$aVisser, Maya 000156610 7102_ $$14009$$2730$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicología Básica 000156610 7102_ $$14009$$2735$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Psicolog.Evolut.Educac 000156610 773__ $$g131 (2025), 106527 [10 pp.]$$pSleep Med.$$tSLEEP MEDICINE$$x1389-9457 000156610 8564_ $$s2296574$$uhttps://zaguan.unizar.es/record/156610/files/texto_completo.pdf$$yVersión publicada 000156610 8564_ $$s2405929$$uhttps://zaguan.unizar.es/record/156610/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000156610 909CO $$ooai:zaguan.unizar.es:156610$$particulos$$pdriver 000156610 951__ $$a2025-10-17-14:27:58 000156610 980__ $$aARTICLE