156646 20251017144551.0 doi 10.1007/s41999-025-01193-0 sideral 143951 ART-2025-143951 eng Monfà, Ramon The impact of a multifaceted intervention on antibiotic use for common infections in nursing homes in Spain. A before and after study 2025 Access copy available to the general public Unrestricted Purpose The aim of this study was to assess the impact of a multifaceted intervention aimed at nursing home staff on antibiotic use and hygiene elements for nursing home residents with common infections. Methods Before-and-after study carried out in nursing homes in five areas of Spain. Nursing staff registered residents with common infections and documented hygiene practices over three months, before and after a 2-h educational intervention in autumn 2023. The intervention focused on the initial registration results, antibiotic guidelines, infection prevention, and management strategies for nursing homes. Indicators for potentially unnecessary antibiotic use and non-first-line antibiotics were developed, and results from both registration periods (Feb-Apr 2023 and Feb-Apr 2024) were compared to assess impact. Results Of 34 nursing homes, 23 completed the intervention and the two registrations (67.6%). Staff reported 1003 infections in the first registration and 789 in the second. The overall antibiotic prescription rate was 84.6%. Potentially inappropriate antibiotic use for urinary tract infections decreased from 70.3 to 59.9% (P < 0.005) and use for respiratory infections dropped from 78.1 to 62.7% (P < 0.001), with inappropriate use decreasing from 46.3 to 31% (P < 0.001). The mean duration of antibiotics for cystitis reduced from 7 to 5.4 days (P < 0.05). The intervention had no impact on hygiene practices. Conclusion Potentially unnecessary antibiotic use was lower after the intervention, whereas hygiene practices were unchanged. A more intensive, multifaceted educational approach is needed for a greater impact. info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion García-Sangenís, Ana Morros, Rosa Zárate Sáez, Carlota Manuela Mateos-Nozal, Jesús Vaquero Pinto, María N. Sáez Bejar, Carmen López Pérez, Elena Rodríguez Jiménez, Consuelo Magallón-Botaya, Rosa Universidad de Zaragoza (orcid)0000-0002-5494-6550 Matovelle, Priscila Navarro Sanmartín, Alicia Llor, Carl 1007 610 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Medicina EUROPEAN GERIATRIC MEDICINE EUROPEAN GERIATRIC MEDICINE 1878-7649 528421 http://zaguan.unizar.es/record/156646/files/texto_completo.pdf Versión publicada 2069252 http://zaguan.unizar.es/record/156646/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:156646 articulos driver 2025-10-17-14:11:50 ARTICLE