000160881 001__ 160881 000160881 005__ 20251017144556.0 000160881 0247_ $$2doi$$a10.1177/20552076251334442 000160881 0248_ $$2sideral$$a144075 000160881 037__ $$aART-2025-144075 000160881 041__ $$aeng 000160881 100__ $$aMartínez-García, Laura$$uUniversidad de Zaragoza 000160881 245__ $$aRegulEm, a smartphone app based on the unified protocol for the transdiagnostic treatment of emotional disorders: description of its application in blended format in a clinical case 000160881 260__ $$c2025 000160881 5060_ $$aAccess copy available to the general public$$fUnrestricted 000160881 5203_ $$aObjective The Spanish national health system (SNHS) faces significant barriers to psychological care, such as long waiting lists and a lack of human resources. In addition, with emotional disorders being the most prevalent disorders worldwide, and less than half of those affected receiving proper treatment, there is an urgent need for new treatment alternatives for this group of disorders. The Unified Protocol (UP) is presented as a possible solution that has amply demonstrated its efficacy in different formats and contexts. Another promising alternative involves the use of blended formats, combining face-to-face UP sessions with a UP-based application. This manuscript focuses on the description of RegulEm, a UP-based application developed following a participatory design approach. In addition, a case example of receiving UP in a blended format in a specialized mental health unit of the SNHS is presented. Methods The following components of RegulEm are described: content and exercises of the modules; aesthetics and multimedia-based content; intervention delivery; testimonials section; emotional and motivation assessment; exposure hierarchy for guided in vivo and imaginal exposure; emergency button and Gamification. A case example of a 26-year-old male patient with anxiety and depressive symptoms receiving UP in a blended format in a specialized mental health unit of the SNHS is presented. Results The user showed improvements in emotional regulation skills, anxiety, and depressive symptoms over time, though stressors remained. RegulEm allowed independent progress between face-to-face UP sessions, but low internalization of some content emphasized the importance of therapist guidance in face-to-face sessions. User feedback highlighted satisfaction with the intervention but improvement proposals for RegulEm were identified, such as simplifying emotional exposure exercises. Conclusion This manuscript describes in detail the first UP-based smartphone application's components and illustrates important implications, such as enabling users to progress at their own pace between sessions and advancing more quickly in the intervention. 000160881 536__ $$9info:eu-repo/grantAgreement/ES/DGA/S31-23R$$9info:eu-repo/grantAgreement/ES/ISCIII-FEDER/PI20-00697 000160881 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 000160881 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000160881 700__ $$aBelaunzaran Mendizabal, Jon 000160881 700__ $$aSantos Goñi, María Asunción 000160881 700__ $$aMiralles, Ignacio 000160881 700__ $$0(orcid)0000-0002-7293-318X$$aOsma, Jorge$$uUniversidad de Zaragoza 000160881 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló. 000160881 773__ $$g11 (2025), [16 pp.]$$tDigital Health$$x2055-2076 000160881 8564_ $$s1452766$$uhttps://zaguan.unizar.es/record/160881/files/texto_completo.pdf$$yVersión publicada 000160881 8564_ $$s2340563$$uhttps://zaguan.unizar.es/record/160881/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000160881 909CO $$ooai:zaguan.unizar.es:160881$$particulos$$pdriver 000160881 951__ $$a2025-10-17-14:13:13 000160881 980__ $$aARTICLE