000160925 001__ 160925
000160925 005__ 20251017144626.0
000160925 0247_ $$2doi$$a10.1002/fsn3.70097
000160925 0248_ $$2sideral$$a144035
000160925 037__ $$aART-2025-144035
000160925 041__ $$aeng
000160925 100__ $$aContreras-Solís, Ignacio
000160925 245__ $$aMicroencapsulated Linseed Oil Supplementation Modifies Lipid Profile and Improves Luteal Function in Dairy Sheep
000160925 260__ $$c2025
000160925 5060_ $$aAccess copy available to the general public$$fUnrestricted
000160925 5203_ $$aPolyunsaturated fatty acids omega 3 (PUFA‐ω3) have been shown to modulate reproductive events such as ovarian follicular and luteal development, steroid and prostaglandin synthesis, and oocyte/embryo quality in different species. These effects could be exploited to support pregnancy and avoid early embryo losses that could occur in dairy sheep breeding. This study aimed to evaluate the effectiveness of dietary supplementation of microencapsulated/by‐passed linseed oil (LO) on ovarian function, embryo implantation rates, and lipid profiles of Sarda ewes during their early pregnancy. Our results demonstrated that the intake of microencapsulated LO at a level of 4.0% of fresh matter increased the plasmatic concentrations of PUFASω3 (p < 0.01) and progesterone (p < 0.05), as well as cholesterol (p < 0.01), triglyceride (p < 0.001), high‐density lipoprotein (p < 0.001), and non‐esterified fatty acids (p < 0.05). The percentage of ewes in estrus, ovulation rate per mated ewe, number of embryos per ewe, and pregnancy rates were similar between treated and control groups. In conclusion, dietary supplementation of by‐pass LO during the preimplantation period increased PUFAS‐ω3 distribution at systemic and local levels. Also, this supplementation modified the ewe's lipid profile and improved luteal function with a possible positive effect on embryo‐maternal crosstalk and embryo implantation rate during and after the maternal recognition of pregnancy.
000160925 536__ $$9info:eu-repo/grantAgreement/EC/H2020/832326/EU/Effect of polyinsatured fatty acids omega-3 (PUFAS n-3) supplementation during early embryo development on embryo viability in (mammals) sheep./NUTREPHEALTH$$9This project has received funding from the European Union’s Horizon 2020 research and innovation program under grant agreement No H2020 832326-NUTREPHEALTH
000160925 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000160925 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000160925 700__ $$aPorcu, Cristian
000160925 700__ $$aSotgiu, Francesca Daniela
000160925 700__ $$aPasciu, Valeria
000160925 700__ $$aTodorova, Neda
000160925 700__ $$aMara, Laura
000160925 700__ $$aChessa, Fabrizio
000160925 700__ $$aAddis, Margherita
000160925 700__ $$aFiori, Myriam
000160925 700__ $$aMolle, Giovanni
000160925 700__ $$aDattena, Maria
000160925 700__ $$aGonzalez-Bulnes, Antonio
000160925 700__ $$0(orcid)0000-0003-2827-3054$$aAbecia, José Alfonso$$uUniversidad de Zaragoza
000160925 700__ $$aBerlinguer, Fiammetta
000160925 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000160925 773__ $$g13, 4 (2025), 10 pp.$$pFood sci. nutr.$$tFood Science and Nutrition$$x2048-7177
000160925 8564_ $$s504199$$uhttps://zaguan.unizar.es/record/160925/files/texto_completo.pdf$$yVersión publicada
000160925 8564_ $$s2480121$$uhttps://zaguan.unizar.es/record/160925/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000160925 909CO $$ooai:zaguan.unizar.es:160925$$particulos$$pdriver
000160925 951__ $$a2025-10-17-14:24:26
000160925 980__ $$aARTICLE