000160944 001__ 160944 000160944 005__ 20251017144643.0 000160944 0247_ $$2doi$$a10.1371/journal.pone.0318512 000160944 0248_ $$2sideral$$a144018 000160944 037__ $$aART-2025-144018 000160944 041__ $$aeng 000160944 100__ $$0(orcid)0000-0001-9726-3250$$aNavarro-Haro, María V.$$uUniversidad de Zaragoza 000160944 245__ $$aImplementation of two transdiagnostic interventions based on emotional regulation for professionals who treat alcohol addiction in the Spanish mental health system: A multicenter mixed methods pilot study protocol 000160944 260__ $$c2025 000160944 5060_ $$aAccess copy available to the general public$$fUnrestricted 000160944 5203_ $$aEmotional dysregulation has been considered a transdiagnostic factor and an important determinant of craving and relapse in alcohol addiction. Dialectical Behavior Therapy (DBT) and the Unified Protocol (UP) are two transdiagnostic emotional regulation programs with good efficacy in improving alcohol addiction severity. However, an important barrier encountered when implementing evidence-based interventions in drug addiction services is the inadequate training received by professionals. This study aims to evaluate the effect of a dissemination and pilot implementation initiative of DBT and UP among professionals treating alcohol addiction in the national Spanish healthcare system. Methods: The study will be conducted in two phases using a mixed methods design. In phase 1, two 3-day training workshops (DBT and UP; 40 hours total) will be provided by experts to at least 130 healthcare workers from three Spanish regions. Participants will be randomly assigned to receive either DBT or UP training first, followed by the other. The study will include a range of quantitative outcomes including beliefs about alcohol abuse, burnout, self-efficacy, attitudes towards evidence-based interventions, organizational variables, acceptability and intention to use the interventions, barriers to implementation, and knowledge acquisition. The appropriateness of the interventions in real community settings will be qualitatively assessed. In phase 2, at least 30 trained professionals will be randomly assigned to implement DBT or/and UP 3-month group interventions in their workplaces with alcohol addiction patients. Quantitative outcomes will include acceptability, feasibility, appropriateness, fidelity and sustainability of the interventions, barriers to implementation, as well as qualitative descriptions of barriers and facilitators during the implementation process. Discussion: To our knowledge, this is the first study to evaluate a pilot implementation of transdiagnostic psychological interventions based on emotion regulation to treat alcohol addiction. Findings of this study will inform of factors influencing the successful implementation of DBT and UP in community-based addiction services. Trial registration: ClinicalTrials.gov NCT06366100. 000160944 536__ $$9info:eu-repo/grantAgreement/ES/DGA/S31-23R$$9info:eu-repo/grantAgreement/ES/MSCBS/Plan Nacional sobre Drogas 2023I060 000160944 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es 000160944 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000160944 700__ $$aAbanades-Morillo, Alba$$uUniversidad de Zaragoza 000160944 700__ $$0(orcid)0000-0002-2437-1207$$aPéris-Baquero, Óscar$$uUniversidad de Zaragoza 000160944 700__ $$0(orcid)0000-0003-2082-8115$$aMartínez-Borba, Verónica$$uUniversidad de Zaragoza 000160944 700__ $$aCrespo-Delgado, Elena 000160944 700__ $$aBaquero-Escribano, Abel 000160944 700__ $$aMasferrer-Boix, Laura 000160944 700__ $$0(orcid)0000-0002-7293-318X$$aOsma, Jorge$$uUniversidad de Zaragoza 000160944 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló. 000160944 773__ $$g20, 5 (2025), e0318512 [18 pp.]$$pPLoS One$$tPLoS ONE$$x1932-6203 000160944 8564_ $$s1044022$$uhttps://zaguan.unizar.es/record/160944/files/texto_completo.pdf$$yVersión publicada 000160944 8564_ $$s2467164$$uhttps://zaguan.unizar.es/record/160944/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000160944 909CO $$ooai:zaguan.unizar.es:160944$$particulos$$pdriver 000160944 951__ $$a2025-10-17-14:32:54 000160944 980__ $$aARTICLE