161768 20251107103407.0 doi 10.1111/sms.70090 sideral 144438 ART-2025-144438 eng Sánchez-Valdepeñas, Juan Effects of different velocity loss thresholds in full squat with and without blood flow restriction on strength gains, neuromuscular adaptations, and muscle hypertrophy 2025 Access copy available to the general public Unrestricted ABSTRACTThis study aimed to analyze the effects of four full‐squat (SQ) training programs that differed in the blood flow condition [free flow (FF) versus restricted (BFR)] and in the velocity loss (VL) induced within the set (20% vs. 40%) on strength gains and muscle hypertrophy. Fifty‐two strength‐trained men followed an 8‐week (16 sessions) SQ training program from 55% to 70% 1‐repetition maximum (1RM) (FF20: n = 14; BFR20: n = 13; FF40: n = 12; BFR40: n = 13). The number of sets n = 13 per session and the inter‐set recovery periods (2 min) were matched between groups. A 50% arterial occlusion pressure was applied and maintained during the inter‐set recovery for BFR groups. The following tests were carried out before and after the training intervention: (1) cross‐sectional area of the vastus lateralis (ACSA); (2) countermovement jump; (3) progressive loading SQ test; and (4) fatigue SQ test. No significant BFR × VL × time interactions were observed. For 1RM and strength‐derived outcomes from the progressive loading test, significant VL × time interactions (p = 0.01–0.05) in favor of 20% VL groups were found. Regarding jump performance, a significant VL × time interaction (p = 0.02) also favored the 20% VL groups. A BFR × time interaction (p = 0.02) was observed in favor of the BFR condition for ACSA. Prescribing a certain level of effort through VL results in similar jump and strength performance improvements, regardless of blood flow condition, with optimal gains achieved at a moderate VL threshold (20%). Additionally, the BFR condition maximized muscle hypertrophy compared to FF, making it a valuable strategy for muscle growth. info:eu-repo/grantAgreement/ES/ISCIII/CB16-10-00477 info:eu-repo/grantAgreement/ES/MICINN/FPU19/00891 info:eu-repo/grantAgreement/ES/MICINN/PID2020-117915RA-I00 info:eu-repo/semantics/embargoedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Asín-Izquierdo, Iván Universidad de Zaragoza (orcid)0000-0002-0541-2050 Cornejo-Daza, Pedro Jesús Universidad de Zaragoza (orcid)0000-0002-2737-5270 Mariscal, Gonzalo Romagnoli, Ruggero Alcazar, Julian González-Badillo, Juan José Saez de Villarreal, Eduardo Pareja-Blanco, Fernando 3001 187 Universidad de Zaragoza Dpto. Expres.Music.Plást.Corp. Área Didáctica Expres.Corporal 35, 6 (2025), e70090 [12 pp.] Scand. j. med. sci. sports Scandinavian Journal of Medicine and Science in Sports 0905-7188 394210 http://zaguan.unizar.es/record/161768/files/texto_completo.pdf Postprint info:eu-repo/date/embargoEnd/2026-05-25 1654254 http://zaguan.unizar.es/record/161768/files/texto_completo.jpg?subformat=icon icon Postprint info:eu-repo/date/embargoEnd/2026-05-25 oai:zaguan.unizar.es:161768 articulos driver 2025-11-07-10:32:20 ARTICLE