000162126 001__ 162126
000162126 005__ 20251017144628.0
000162126 0247_ $$2doi$$a10.1002/anie.202507424
000162126 0248_ $$2sideral$$a144741
000162126 037__ $$aART-2025-144741
000162126 041__ $$aeng
000162126 100__ $$aEspañol-Sánchez, Belinda$$uUniversidad de Zaragoza
000162126 245__ $$aLigand‐Controlled Chemoselectivity in the Rhodium‐Catalyzed Synthesis of Pentafulvenes via (2 + 2 + 1) Alkyne Cyclotrimerization
000162126 260__ $$c2025
000162126 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162126 5203_ $$aThe synthesis of pentafulvenes with varied substituents has been efficiently achieved using novel rhodium‐based catalysts via (2 + 2 + 1) alkyne cyclotrimerization. A rational design of the catalyst structure, including pyridonato, NHC, and CO ligands, ensures the alkyne chemoselectivity and prevents the formation of robust rhodium‐fulvene species. Furthermore, the judicious choice of acidity and steric properties of different alkynes enables the preparation of cross‐coupled fulvene derivatives. Stoichiometric and deuteration experiments, as well as DFT calculations, shed light on the reaction mechanism, showing that it includes an initial alkyne deprotonation, two successive alkyne insertions, cyclization, and protonolysis, the first insertion being the rate‐determining step.
000162126 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E42-23R$$9info:eu-repo/grantAgreement/ES/MICINN-FEDER/PID2019-103965GB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/PID2022-137208NB-I00
000162126 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000162126 655_4 $$ainfo:eu-repo/semantics/conferenceObject$$vinfo:eu-repo/semantics/publishedVersion
000162126 700__ $$aMoradell, Jesús
000162126 700__ $$0(orcid)0000-0002-2043-4864$$aGaliana-Cameo, María
000162126 700__ $$aBarrenas, Eduardo
000162126 700__ $$0(orcid)0000-0002-3327-0918$$aPérez-Torrente, Jesús J.$$uUniversidad de Zaragoza
000162126 700__ $$0(orcid)0000-0002-1735-6439$$aPassarelli, Vincenzo
000162126 700__ $$0(orcid)0000-0003-4460-8678$$aCastarlenas, Ricardo
000162126 7102_ $$12010$$2760$$aUniversidad de Zaragoza$$bDpto. Química Inorgánica$$cÁrea Química Inorgánica
000162126 773__ $$g(2025), e202507424 ([6 pp.)$$pAngew. Chem. (Int. ed.)$$tAngewandte Chemie (International ed.)$$x1433-7851
000162126 8564_ $$s2206214$$uhttps://zaguan.unizar.es/record/162126/files/texto_completo.pdf$$yVersión publicada
000162126 8564_ $$s2756988$$uhttps://zaguan.unizar.es/record/162126/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162126 909CO $$ooai:zaguan.unizar.es:162126$$particulos$$pdriver
000162126 951__ $$a2025-10-17-14:25:00
000162126 980__ $$aARTICLE