000162151 001__ 162151
000162151 005__ 20251017144653.0
000162151 0247_ $$2doi$$a10.3390/stresses5020026
000162151 0248_ $$2sideral$$a144728
000162151 037__ $$aART-2025-144728
000162151 041__ $$aeng
000162151 100__ $$aZayani, Zoofa
000162151 245__ $$aExploring Stressors: Impact on Cellular Organelles and Implications for Cellular Functions
000162151 260__ $$c2025
000162151 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162151 5203_ $$aCellular stressors have been demonstrated to exert a substantial influence on the functionality of organelles, thereby impacting cellular homeostasis and contributing to the development of disease pathogenesis. This review aims to examine the impact of diverse stressors, including environmental, chemical, biological, and physical factors, on critical organelles such as the cell membrane, mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and membrane-less organelles. The intricate molecular mechanisms underlying cellular stress responses, encompassing oxidative stress, protein misfolding, and metabolic reprogramming, have the capacity to elicit adaptive responses or culminate in pathological conditions. The interplay between these stressors and organelle dysfunction has been implicated in a myriad of diseases, including neurodegenerative disorders, cancer, metabolic disorders, and immune-related pathologies. A comprehensive understanding of the mechanisms by which organelles respond to stress can offer valuable insights into the development of therapeutic strategies aimed at mitigating cellular damage.
000162151 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000162151 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162151 700__ $$aMatinahmadi, Arash
000162151 700__ $$aTavakolpournegari, Alireza
000162151 700__ $$aBidooki, Seyed Hesamoddin$$uUniversidad de Zaragoza
000162151 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000162151 773__ $$g5, 2 (2025), 26 [42 pp.]$$tStresses$$x2673-7140
000162151 8564_ $$s5126580$$uhttps://zaguan.unizar.es/record/162151/files/texto_completo.pdf$$yVersión publicada
000162151 8564_ $$s2630029$$uhttps://zaguan.unizar.es/record/162151/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162151 909CO $$ooai:zaguan.unizar.es:162151$$particulos$$pdriver
000162151 951__ $$a2025-10-17-14:37:19
000162151 980__ $$aARTICLE