000162206 001__ 162206
000162206 005__ 20251017144608.0
000162206 0247_ $$2doi$$a10.1111/tbed.14062
000162206 0248_ $$2sideral$$a124394
000162206 037__ $$aART-2022-124394
000162206 041__ $$aeng
000162206 100__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, S.$$uUniversidad de Zaragoza
000162206 245__ $$aSerological evidence of SARS-CoV-2 and co-infections in stray cats in Spain
000162206 260__ $$c2022
000162206 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162206 5203_ $$aA new coronavirus known as SARS-CoV-2 emerged in Wuhan in 2019 and spread rapidly to the rest of the world causing the pandemic disease named coronavirus disease of 2019 (COVID-19). Little information is known about the impact this virus can cause upon domestic and stray animals. The potential impact of SARS-CoV-2 has become of great interest in cats due to transmission among domestic cats and the severe phenotypes described recently in a domestic cat. In this context, there is a public health warning that needs to be investigated in relation with the epidemiological role of this virus in stray cats. Consequently, in order to know the impact of the possible transmission chain, blood samples were obtained from 114 stray cats in the city of Zaragoza (Spain) and tested for SARS-CoV-2 and other selected pathogens susceptible to immunosuppression including Toxoplasma gondii, Leishmania infantum, feline leukaemia virus (FeLV) and feline immunodeficiency virus (FIV) from January to October 2020. Four cats (3.51%), based on enzyme-linked immunosorbent assay (ELISA) using the receptor binding domain (RBD) of Spike antigen, were seroreactive to SARS-CoV-2. T. gondii, L. infantum, FeLV and FIV seroprevalence was 12.28%, 16.67%, 4.39% and 19.30%, respectively. Among seropositive cats to SARS-CoV-2, three cats were also seropositive to other pathogens including antibodies detected against T. gondii and FIV (n = 1); T. gondii (n = 1); and FIV and L. infantum (n = 1). The subjects giving positive for SARS-CoV-2 were captured in urban areas of the city in different months: January 2020 (2/4), February 2020 (1/4) and July 2020 (1/4). This study revealed, for the first time, the exposure of stray cats to SARS-CoV-2 in Spain and the existence of concomitant infections with other pathogens including T. gondii, L. infantum and FIV, suggesting that immunosuppressed animals might be especially susceptible to SARS-CoV-2 infection.
000162206 536__ $$9info:eu-repo/grantAgreement/ES/DGA-FEDER/B29-17R$$9info:eu-repo/grantAgreement/ES/DGA-FEDER/E34-R17$$9info:eu-repo/grantAgreement/ES/DGA/LMP58-18$$9info:eu-repo/grantAgreement/ES/ISCIII/COV20-0030$$9info:eu-repo/grantAgreement/ES/MICINN/BFU2016-75633-P$$9info:eu-repo/grantAgreement/ES/MICINN/CTQ2013-44367-C2-2-P$$9info:eu-repo/grantAgreement/ES/MICINN/PID2019-105451GB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/SAF2017-83120-C2-1-R
000162206 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000162206 590__ $$a4.3$$b2022
000162206 591__ $$aVETERINARY SCIENCES$$b7 / 144 = 0.049$$c2022$$dQ1$$eT1
000162206 591__ $$aINFECTIOUS DISEASES$$b42 / 96 = 0.438$$c2022$$dQ2$$eT2
000162206 592__ $$a0.99$$b2022
000162206 593__ $$aMedicine (miscellaneous)$$c2022$$dQ1
000162206 593__ $$aVeterinary (miscellaneous)$$c2022$$dQ1
000162206 593__ $$aImmunology and Microbiology (miscellaneous)$$c2022$$dQ2
000162206 594__ $$a7.4$$b2022
000162206 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000162206 700__ $$aGiner, J.
000162206 700__ $$0(orcid)0000-0002-2646-5733$$aTobajas, A.P.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0003-2555-8425$$aPérez, M.D.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0002-5838-0857$$aGonzález-Ramírez, A.M.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0001-6815-6720$$aMacías-León, J.$$uUniversidad de Zaragoza
000162206 700__ $$aGonzález, A.
000162206 700__ $$0(orcid)0000-0003-2957-1379$$aVerde, M.$$uUniversidad de Zaragoza
000162206 700__ $$aYzuel, A.
000162206 700__ $$0(orcid)0000-0002-3122-9401$$aHurtado-Guerrero, R.
000162206 700__ $$0(orcid)0000-0003-0154-0730$$aPardo, J.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0002-1861-5981$$aSantiago, L.
000162206 700__ $$0(orcid)0000-0002-9600-8116$$aPaño-Pardo, J.R.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0002-8474-2831$$aRuíz, H.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0002-7822-6646$$aLacasta, D.M.$$uUniversidad de Zaragoza
000162206 700__ $$0(orcid)0000-0001-5964-823X$$aSánchez, L.$$uUniversidad de Zaragoza
000162206 700__ $$aMarteles, D.
000162206 700__ $$0(orcid)0000-0001-9333-3055$$aGracia, A.P.
000162206 700__ $$0(orcid)0000-0002-2557-4890$$aFernández, A.$$uUniversidad de Zaragoza
000162206 7102_ $$11011$$2566$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Inmunología
000162206 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000162206 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000162206 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000162206 7102_ $$12008$$2780$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Tecnología de Alimentos
000162206 773__ $$g69 (2022), 1056-1064$$pTransboundary and Emerging Diseases$$tTransboundary and Emerging Diseases$$x1865-1674
000162206 8564_ $$s582071$$uhttps://zaguan.unizar.es/record/162206/files/texto_completo.pdf$$yPostprint
000162206 8564_ $$s951409$$uhttps://zaguan.unizar.es/record/162206/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000162206 909CO $$ooai:zaguan.unizar.es:162206$$particulos$$pdriver
000162206 951__ $$a2025-10-17-14:16:03
000162206 980__ $$aARTICLE