000162213 001__ 162213
000162213 005__ 20251017144613.0
000162213 0247_ $$2doi$$a10.1136/vetreccr-2020-001290
000162213 0248_ $$2sideral$$a121542
000162213 037__ $$aART-2020-121542
000162213 041__ $$aeng
000162213 100__ $$0(orcid)0000-0001-6209-4282$$aVillanueva-Saz, S.$$uUniversidad de Zaragoza
000162213 245__ $$aBisalbuminemia in a dog with leishmaniosis after anti-Leishmania therapeutic protocol administration: a rare condition detected in the electrophoretogram
000162213 260__ $$c2020
000162213 5203_ $$aA 5-year-old spayed, crossbred female dog was referred for a unilateral nosebleed of 4 months'' duration. Rhinoscopy revealed significant inflammation of the nasal mucosa compatible with severe rhinitis. On the right nostril, the presence of a white patch on the mucosa was observed and a biopsy was taken. Histopathology revealed a granulomatous inflammation with the presence of neutrophils and lymphocytes. Some macrophages contained small oval microorganisms compatible with Leishmania species. The presence of Leishmania infantum was confirmed by specific immunohistochemistry, showing stained intracellular microorganisms. Abnormal clinicopathological findings included mild anaemia and hyperglobulinemia with polyclonal gammopathy. Moderate amount of antibodies to L. infantum were detected by ELISA in serum. An anti-Leishmania therapeutic protocol was established with allopurinol and meglumine antimoniate, and 4 months later, a follow-up examination was performed showing improvements in laboratory parameters with the exception of the presence of bisalbuminemia.
000162213 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000162213 592__ $$a0.165$$b2020
000162213 593__ $$aVeterinary (miscellaneous)$$c2020$$dQ4
000162213 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162213 700__ $$aBalleste, C.
000162213 700__ $$0(orcid)0000-0002-2557-4890$$aFernandez Casasnovas, A.$$uUniversidad de Zaragoza
000162213 700__ $$aYzuel Estevez, A.
000162213 700__ $$0(orcid)0000-0003-2957-1379$$aVerde Arribas, M.T.$$uUniversidad de Zaragoza
000162213 7102_ $$11012$$2315$$aUniversidad de Zaragoza$$bDpto. Farmac.Fisiol.y Med.L.F.$$cÁrea Farmacología
000162213 7102_ $$11009$$2617$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Medicina y Cirugía Animal
000162213 773__ $$g8, 4 (2020), e001290 [6 pp.]$$pVet. rec. case rep.$$tVeterinary Record Case Reports$$x2052-6121
000162213 8564_ $$s802176$$uhttps://zaguan.unizar.es/record/162213/files/texto_completo.pdf$$yVersión publicada
000162213 8564_ $$s3352654$$uhttps://zaguan.unizar.es/record/162213/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162213 909CO $$ooai:zaguan.unizar.es:162213$$particulos$$pdriver
000162213 951__ $$a2025-10-17-14:18:12
000162213 980__ $$aARTICLE