162242 20251017144644.0 doi 10.3389/fpsyg.2025.1540530 sideral 144752 ART-2025-144752 deu Sánchez-Recio, Raquel Universidad de Zaragoza (orcid)0000-0002-0078-0663 Self-reported health and depression among EIRA cohort: a moderated mediation model of sex and perceived social support 2025 Access copy available to the general public Unrestricted The positive relationship between health and good perceived social support has been widely demonstrated in the scientific literature. It is known that having a good social support influences the proper maintenance of health even as a protective factor, besides being a good predictor in the recovery of health during a disease process, influencing differently men and women.AimThis project aims to study the moderating effects of perceived social support in the relationship between depression and self-perceived health according to gender, after a complex multiple-risk intervention was carried out in patients of primary health care with low social support.MethodsA cluster randomized clinical trial was developed in the subgroup of patients included in phase 3 of the EIRA project. CONSORT recommendations were followed to present the results. To determine the mediating effect between social support and self-perceived health, three regression analyses were carried out using the procedure designed by Hayes through the PROCESS macro for SPSS.Results3,062 people (54.9% women) participated in the study. Men reported experiencing more social support and self-perceived health (p < 0.001) than women at the beginning of the study, but women reported higher social support at post-intervention. Moderation analyses showed that, post-intervention, those women (bsimple = −2.9867, p < 0.001) and males (bsimple = −1.4337, p < 0.001) who scored lower in depression reported higher social support.ConclusionIn primary care, it is necessary to encourage intervention strategies that promote social networks as a key element of positive action aimed at maintaining and improving the population’s health, especially in adults and more specifically in women.Clinical trial registrationClinicalTrials.gov, identifier NCT03136211. info:eu-repo/grantAgreement/ES/ISCIII-MINECO/PI15/01072 info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0003 info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0005 info:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0002 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0004 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0006 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0008 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0009 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0010 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0012 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0013 iinfo:eu-repo/grantAgreement/ES/ISCIII-RedIAPP/RD16-0007-0015 info:eu-repo/grantAgreement/ES/ISCIII/RD12-0005-0001 info:eu-repo/grantAgreement/ES/ISCIII/RD16-0007-0001 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-00114 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-00565 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-00762 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-00896 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-01133 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-01151 info:eu-repo/grantAgreement/ES/MINECO/ISCIII/PI15-01412 info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Oliván-Blázquez, Bárbara Universidad de Zaragoza (orcid)0000-0001-6565-9699 Méndez-López, Fátima Universidad de Zaragoza (orcid)0000-0002-6409-9041 Gascón-Santos, Santiago Universidad de Zaragoza (orcid)0000-0002-3723-0673 Martí-Lluch, Ruth Zabaleta-Del-Olmo, Edurne Tamayo-Morales, Olaya Maderuelo-Fernández, José A. Casajuana, Marc López-Jiménez, Tomas Motrico, Emma Gómez-Gómez, Irene Sánchez-Pérez, Álvaro Rodero-Cosano, María Luisa Llobera, Joan Bellón, Juan A. Moreno-Peral, Patricia Bolíbar, Bonaventura Recio-Rodríguez, José I. Ramos, Rafel Clavería, Ana 1006 255 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Enfermería 4009 740 Universidad de Zaragoza Dpto. Psicología y Sociología Área Psicología Social 4009 680 Universidad de Zaragoza Dpto. Psicología y Sociología Área Person.Eval.Trat.Psicoló. 16 (2025), 12 pp. Front. psychol. Frontiers in Psychology 1664-1078 723730 http://zaguan.unizar.es/record/162242/files/texto_completo.pdf Versión publicada 2497920 http://zaguan.unizar.es/record/162242/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:162242 articulos driver 2025-10-17-14:33:23 ARTICLE