000162375 001__ 162375
000162375 005__ 20251017144651.0
000162375 0247_ $$2doi$$a10.1093/ptj/pzaf057
000162375 0248_ $$2sideral$$a144906
000162375 037__ $$aART-2025-144906
000162375 041__ $$aeng
000162375 100__ $$aNúñez-Cortés, Rodrigo
000162375 245__ $$aOptimal Dose of Aerobic Exercise Programs to Reduce Pain Intensity and Improve Health Status in Patients With Fibromyalgia: A Dose-Response Meta-Analysis
000162375 260__ $$c2025
000162375 5203_ $$aObjective
The purpose of this study was to examine the dose-response relationship between aerobic exercise programs and changes in pain intensity and health status in patients with fibromyalgia.
Data Sources
Data sources for this study were PubMed, PEDro, Google Scholar, and EBSCO from inception until February 9, 2024.
Study Selection
Randomized controlled trials (RCTs) of aerobic exercise in patients with a clinical diagnosis of fibromyalgia were included.
Data Extraction
Outcome measures were pain intensity (Visual Analog Scale) and health status (Fibromyalgia Impact Questionnaire (FIQ)). The dose-response relationship was evaluated using a restricted cubic spline model.
Data Synthesis
Twenty-three RCTs were included. The meta-analysis showed a significant improvement in pain intensity and functional status. A minimum dose of 50 min per week standardized mean difference (SMD = −0.67; 95% CI = −0.70 to −0.65) and a total duration of 600 min (SMD = −0.65; 95% CI = −0.69 to −0.62) were estimated to effectively reduce pain intensity. The maximum effect was achieved with 90 min per week (SMD = −1.14; 95% CI = −1.19 to −1.09) and 1200 min total duration (SMD = −1.08; 95%CI = −1.13 to −1.02). Additionally, a minimum dose of 65 min per week (SMD = −0.62; 95% CI = −0.6 to −0.69) and a total duration of 950 min (SMD = −0.61; 95% CI = −0.60 to −0.67) were estimated to effectively reduce the FIQ score. While the maximum effect was obtained with 150 min per week (SMD = −1.77; 95% CI = −1.89 to −1.65) and 3000 min of total duration (SMD = −1.43; 95% CI = −1.54 to −1.31).
Conclusion
These findings may be useful in optimizing the minimal dose of aerobic exercise to achieve health improvements in people with fibromyalgia.
000162375 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000162375 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162375 700__ $$aSuso-Martí, Luis
000162375 700__ $$aAlmonacid-Lleida, Javier
000162375 700__ $$aSalazar-Méndez, Joaquín
000162375 700__ $$0(orcid)0000-0002-7865-3429$$aLópez-Bueno, Rubén
000162375 700__ $$aCruz-Montecinos, Carlos
000162375 700__ $$aAndersen, Lars L
000162375 700__ $$aRamírez-Vélez, Robinson
000162375 700__ $$aCalatayud, Joaquín
000162375 773__ $$g105, 6 (2025), [12 pp.]$$pPhys. ther.$$tPhysical Therapy$$x0031-9023
000162375 8564_ $$s1981569$$uhttps://zaguan.unizar.es/record/162375/files/texto_completo.pdf$$yVersión publicada
000162375 8564_ $$s2437023$$uhttps://zaguan.unizar.es/record/162375/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162375 909CO $$ooai:zaguan.unizar.es:162375$$particulos$$pdriver
000162375 951__ $$a2025-10-17-14:36:30
000162375 980__ $$aARTICLE