000162447 001__ 162447
000162447 005__ 20251017144644.0
000162447 0247_ $$2doi$$a10.3390/jimaging11080257
000162447 0248_ $$2sideral$$a144952
000162447 037__ $$aART-2025-144952
000162447 041__ $$aeng
000162447 100__ $$0(orcid)0009-0006-7694-8086$$aArcas-Carbonell, María
000162447 245__ $$aA Novel Method for Analysing the Curvature of the Anterior Lens: Multi-Radial Scheimpflug Imaging and Custom Conic Fitting Algorithm
000162447 260__ $$c2025
000162447 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162447 5203_ $$aThis study describes and validates a novel method for assessing anterior crystalline lens curvature along vertical and horizontal meridians using radial measurements derived from Scheimpflug imaging. The aim was to evaluate whether pupil diameter (PD), anterior lens curvature, and anterior chamber depth (ACD) change during accommodation and whether these changes are age-dependent. A cross-sectional study was conducted on 104 right eyes from healthy participants aged 21–62 years. Sixteen radial images per eye were acquired using the Galilei Dual Scheimpflug Placido Disk Topographer under four accommodative demands (0, 1, 3, and 5 dioptres (D)). Custom software analysed lens curvature by calculating eccentricity in both meridians. Participants were analysed as a total group and by age subgroups. Accommodative amplitude and monocular accommodative facility were inversely correlated with age. Both PD and ACD significantly decreased with higher accommodative demands and age. Relative eccentricity decreased under accommodation, indicating increased lens curvature, especially in younger participants. Significant curvature changes were detected in the horizontal meridian only, although no statistically significant differences between meridians were found overall. The vertical meridian showed slightly higher eccentricity values, suggesting that it remained less curved. By enabling detailed, meridionally stratified in vivo assessment of anterior lens curvature, this novel method provides a valuable non-invasive approach for characterizing age-related biomechanical changes during accommodation. The resulting insights enhance our understanding of presbyopia progression, particularly regarding the spatial remodelling of the anterior lens surface.
000162447 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000162447 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162447 700__ $$0(orcid)0000-0003-2710-1875$$aOrduna-Hospital, Elvira$$uUniversidad de Zaragoza
000162447 700__ $$aMechó-García, María
000162447 700__ $$0(orcid)0000-0003-1234-9712$$aFernández-Espinosa, Guisela$$uUniversidad de Zaragoza
000162447 700__ $$0(orcid)0000-0002-5621-1937$$aSanchez-Cano, Ana$$uUniversidad de Zaragoza
000162447 7102_ $$12002$$2647$$aUniversidad de Zaragoza$$bDpto. Física Aplicada$$cÁrea Óptica
000162447 773__ $$g11, 8 (2025), 257 [20 pp.]$$tJOURNAL OF IMAGING$$x2313-433X
000162447 8564_ $$s4395048$$uhttps://zaguan.unizar.es/record/162447/files/texto_completo.pdf$$yVersión publicada
000162447 8564_ $$s2431988$$uhttps://zaguan.unizar.es/record/162447/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162447 909CO $$ooai:zaguan.unizar.es:162447$$particulos$$pdriver
000162447 951__ $$a2025-10-17-14:33:16
000162447 980__ $$aARTICLE