162467 20260227124019.0 doi 10.3390/healthcare13172094 sideral 145018 ART-2025-145018 eng Lapuente-Hernández, Diego Universidad de Zaragoza (orcid)0000-0002-6506-6081 Home Physical Exercise Interventions in Chronic Non-Specific Low Back Pain: Systematic Review and Multivariate Meta-Analysis 2025 Access copy available to the general public Unrestricted Background/Objectives: Low back pain is considered one of the leading causes of disability. Up to 90% of cases are classified as non-specific, which, if prolonged for at least 12 weeks, is considered non-specific chronic low back pain (NSCLBP). Physical exercise is one of the selected treatments for NSCLBP. Interest in the use of remote interventions has recently emerged. The main objective was to analyze the effect of home exercise interventions to reduce pain intensity and functional disability in individuals with NSCLBP. Methods: A systematic review was conducted in April 2024. Both multivariate and univariate meta-analysis was performed with the difference before and after treatment, adjusting both models with a meta-regression that included the covariates age and body mass index (BMI). Heterogeneity was analyzed with Cochran’s Q test as well as with the I2 estimator, and effect size was calculated with Hedges’G. Results: A total of six studies, with moderate–high methodological quality and a heterogeneous risk of bias, were included. There was a statistically significant pre-/post-treatment effect on functional disability (moderate effect: Hedge’s g = 0.69, p = 0.018) and pain intensity (large effect: Hedge’s g = 1.11, p = 0.007) in both univariate and multivariate (moderate effect: Hedge’s g = 0.77) meta-analyses when comparing unsupervised home exercise with supervised in-person exercise, in favor of the latter. This effect was significantly moderated by BMI (p = 0.003 for both outcomes) negatively. Conclusions: Unsupervised home exercise appears to be less effective than supervised in-person exercise in effectively reducing pain intensity and functional disability in the short term in individuals with NSCLBP. info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Gil-Calvo, Marina (orcid)0000-0003-4792-1782 Cuenca-Zaldívar, Juan Nicolás Carcasona-Otal, Alberto Universidad de Zaragoza (orcid)0009-0003-8000-7084 Herrero, Pablo Universidad de Zaragoza (orcid)0000-0002-9201-0120 Matute-Llorente, Ángel Universidad de Zaragoza (orcid)0000-0001-8500-1667 1006 245 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Educación Física y Depor. 1006 413 Universidad de Zaragoza Dpto. Fisiatría y Enfermería Área Fisioterapia 13, 17 (2025), 2094 [20 pp.] Healthcare (Basel) Healthcare (Switzerland) 2227-9032 1005856 http://zaguan.unizar.es/record/162467/files/texto_completo.pdf Versión publicada 2498174 http://zaguan.unizar.es/record/162467/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:162467 articulos driver 2026-02-27-12:39:22 ARTICLE