000162541 001__ 162541
000162541 005__ 20260112133140.0
000162541 0247_ $$2doi$$a10.21037/jtd-23-1973
000162541 0248_ $$2sideral$$a145063
000162541 037__ $$aART-2024-145063
000162541 041__ $$aeng
000162541 100__ $$aFuentes-Martín, Álvaro
000162541 245__ $$aImpact of radiological follow-up frequency on resected lung cancer: a propensity score matching analysis
000162541 260__ $$c2024
000162541 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162541 5203_ $$aBackground: Despite advances in lung cancer treatment and the subsequent improvement in oncological outcomes, the optimal frequency of radiological follow-up remains unclear. Current recommendations lack consensus and do not consider individual patient characteristics and tumor factors. This study aimed to examine the impact of radiological follow-up frequency on oncological outcomes following lung cancer resection.
Methods: A prospective multicenter study, involving patients who underwent anatomical lung resection in the GEVATS database between December 2016 and March 2018. The relationship between surveillance frequency and oncological outcomes was evaluated. Two groups were established based on follow-up frequency: low frequency (LF) and high frequency (HF). Subgroup analyses were performed based on tumor stage, histology, lymphadenectomy, and adjuvant therapy. Propensity score matching (PSM) was applied to balance the groups.
Results: A total of 1,916 patients were included in the study, LF 444 (23.17%), HF 1,472 (76.83%). Factors associated with HF surveillance included higher stage, adjuvant chemotherapy and adjuvant radiotherapy. Subanalyses were performed after PSM for various factors, revealing significant differences between LF and HF groups in cancer-specific survival among who received adjuvant therapy {LF 53.021 months [95% confidence interval (CI): 48.622–57.421] vs. HF 58.836 months (95% CI: 55.343–62.330); HR 0.453, 95% CI: 0.242–0.849; P=0.013}, as well as overall survival for patients with squamous cell carcinoma [LF 54.394 months (95% CI: 51.424–57.364) vs. HF 61.578 months (95% CI: 59.091–64.065); HR 0.491, 95% CI: 0.299–0.806; P=0.005] and those who received adjuvant therapy LF 50.176 months [95% CI: 45.609–54.742) vs. HF 57.189 months (95% CI: 53.599–60.778); HR 0.503, 95% CI: 0.293–0.865; P=0.013].
Conclusions: Findings suggest that high-frequency surveillance only improves survival outcomes in lung cancer patients who received adjuvant treatment or had squamous cell carcinoma. Therefore, future guidelines for lung cancer follow-up should consider individualizing the frequency of radiological surveillance based on patients’ risk profiles.
000162541 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000162541 592__ $$a0.624$$b2024
000162541 590__ $$a1.9$$b2024
000162541 593__ $$aPulmonary and Respiratory Medicine$$c2024$$dQ2
000162541 591__ $$aRESPIRATORY SYSTEM$$b67 / 108 = 0.62$$c2024$$dQ3$$eT2
000162541 594__ $$a3.3$$b2024
000162541 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162541 700__ $$aMartínez-Hernández, Néstor J.
000162541 700__ $$aCabañero Sánchez, Alberto
000162541 700__ $$aFigueroa Almánzar, Santiago
000162541 700__ $$aCall, Sergi
000162541 700__ $$aBolufer, Sergio
000162541 700__ $$aGómez de Antonio, David
000162541 700__ $$aMuñoz Moreno, María Fé
000162541 700__ $$0(orcid)0000-0003-0249-3104$$aEmbun, Raul$$uUniversidad de Zaragoza
000162541 700__ $$aCilleruelo Ramos, Ángel
000162541 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000162541 773__ $$g16, 7 (2024), 4275-4285$$pJ. thorac. dis.$$tJournal of thoracic disease$$x2072-1439
000162541 8564_ $$s362282$$uhttps://zaguan.unizar.es/record/162541/files/texto_completo.pdf$$yVersión publicada
000162541 8564_ $$s2394077$$uhttps://zaguan.unizar.es/record/162541/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162541 909CO $$ooai:zaguan.unizar.es:162541$$particulos$$pdriver
000162541 951__ $$a2026-01-12-12:35:36
000162541 980__ $$aARTICLE