162541 20260217205445.0 doi 10.21037/jtd-23-1973 sideral 145063 ART-2024-145063 eng Fuentes-Martín, Álvaro Impact of radiological follow-up frequency on resected lung cancer: a propensity score matching analysis 2024 Access copy available to the general public Unrestricted Background: Despite advances in lung cancer treatment and the subsequent improvement in oncological outcomes, the optimal frequency of radiological follow-up remains unclear. Current recommendations lack consensus and do not consider individual patient characteristics and tumor factors. This study aimed to examine the impact of radiological follow-up frequency on oncological outcomes following lung cancer resection. Methods: A prospective multicenter study, involving patients who underwent anatomical lung resection in the GEVATS database between December 2016 and March 2018. The relationship between surveillance frequency and oncological outcomes was evaluated. Two groups were established based on follow-up frequency: low frequency (LF) and high frequency (HF). Subgroup analyses were performed based on tumor stage, histology, lymphadenectomy, and adjuvant therapy. Propensity score matching (PSM) was applied to balance the groups. Results: A total of 1,916 patients were included in the study, LF 444 (23.17%), HF 1,472 (76.83%). Factors associated with HF surveillance included higher stage, adjuvant chemotherapy and adjuvant radiotherapy. Subanalyses were performed after PSM for various factors, revealing significant differences between LF and HF groups in cancer-specific survival among who received adjuvant therapy {LF 53.021 months [95% confidence interval (CI): 48.622–57.421] vs. HF 58.836 months (95% CI: 55.343–62.330); HR 0.453, 95% CI: 0.242–0.849; P=0.013}, as well as overall survival for patients with squamous cell carcinoma [LF 54.394 months (95% CI: 51.424–57.364) vs. HF 61.578 months (95% CI: 59.091–64.065); HR 0.491, 95% CI: 0.299–0.806; P=0.005] and those who received adjuvant therapy LF 50.176 months [95% CI: 45.609–54.742) vs. HF 57.189 months (95% CI: 53.599–60.778); HR 0.503, 95% CI: 0.293–0.865; P=0.013]. Conclusions: Findings suggest that high-frequency surveillance only improves survival outcomes in lung cancer patients who received adjuvant treatment or had squamous cell carcinoma. Therefore, future guidelines for lung cancer follow-up should consider individualizing the frequency of radiological surveillance based on patients’ risk profiles. info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 1.9 2024 RESPIRATORY SYSTEM 67 / 108 = 0.62 2024 Q3 T2 0.624 2024 Pulmonary and Respiratory Medicine 2024 Q2 3.3 2024 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Martínez-Hernández, Néstor J. Cabañero Sánchez, Alberto Figueroa Almánzar, Santiago Call, Sergi Bolufer, Sergio Gómez de Antonio, David Muñoz Moreno, María Fé Embun, Raul Universidad de Zaragoza (orcid)0000-0003-0249-3104 Cilleruelo Ramos, Ángel 1013 090 Universidad de Zaragoza Dpto. Cirugía Área Cirugía 16, 7 (2024), 4275-4285 J. thorac. dis. Journal of thoracic disease 2072-1439 362282 http://zaguan.unizar.es/record/162541/files/texto_completo.pdf Versión publicada 2394077 http://zaguan.unizar.es/record/162541/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:162541 articulos driver 2026-02-17-20:17:35 ARTICLE