000162542 001__ 162542
000162542 005__ 20260107185710.0
000162542 0247_ $$2doi$$a10.1016/j.arbr.2021.10.005
000162542 0248_ $$2sideral$$a145068
000162542 037__ $$aART-2021-145068
000162542 041__ $$aeng
000162542 100__ $$aAguinagalde, Borja
000162542 245__ $$aVATS lobectomy morbidity and mortality is lower in patients with the same ppoDLCO: Analysis of the database of the Spanish Video-Assisted Thoracic Surgery Group
000162542 260__ $$c2021
000162542 5203_ $$aIntroduction: Measuring predicted post-operative diffusion capacity of the lung for carbon monoxide (ppoDLCO) is essential to determine patient operability and to stratify the risk of patients who are candidates for major lung cancer surgery. Studies that established surgical risk variables were based on open surgery series. The aim of our study was to analyze morbidity and mortality as a function of ppoDLCO and to compare its behavior in open and video-assisted thoracic surgery (VATS).
Methods: We compared 90-day mortality and morbidity in patients undergoing open surgery versus VATS as a function of decline in ppoDLCO. Propensity score matching (using age, ASA, arterial vascular disease, BMI, gender, stage, ppoDLCO, and ppoFEV1) was applied to create comparable open surgery and VATS groups.
Results: Of 2,530 patients with lung cancer and ppoDLCO values, a sample of 1,624 (812 per group) was obtained after score matching. The relative risk of mortality associated with thoracotomy in patients with ppoDLCO < 60 is 2.66 (p < 0.02) compared to VATS. The risk of thoracotomy in terms of overall and cardiac and respiratory morbidity is higher than that of VATS for almost all ppoDLCO values.
Conclusions: Major resection by VATS shows lower morbidity and mortality in patients with the same ppoDLCO. A steady rise in the risk of mortality begins to occur at higher ppoDLCO values in thoracotomy (∼60) than in VATS (∼45).
000162542 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000162542 590__ $$a6.333$$b2021
000162542 591__ $$aRESPIRATORY SYSTEM$$b14 / 66 = 0.212$$c2021$$dQ1$$eT1
000162542 592__ $$a0.262$$b2021
000162542 593__ $$aPulmonary and Respiratory Medicine$$c2021$$dQ3
000162542 594__ $$a2.0$$b2021
000162542 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162542 700__ $$aInsausti, Asier
000162542 700__ $$aLopez, Iker
000162542 700__ $$aSanchez, Laura
000162542 700__ $$aBolufer, Sergio
000162542 700__ $$0(orcid)0000-0003-0249-3104$$aEmbun, Raul$$uUniversidad de Zaragoza
000162542 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000162542 773__ $$g57, 12 (2021), 750-756$$pArch. bronconeumol.$$tArchivos de Bronconeumologia$$x0300-2896
000162542 8564_ $$s1560702$$uhttps://zaguan.unizar.es/record/162542/files/texto_completo.pdf$$yVersión publicada
000162542 8564_ $$s1894453$$uhttps://zaguan.unizar.es/record/162542/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162542 909CO $$ooai:zaguan.unizar.es:162542$$particulos$$pdriver
000162542 951__ $$a2026-01-07-18:55:42
000162542 980__ $$aARTICLE