000162580 001__ 162580
000162580 005__ 20251017144620.0
000162580 0247_ $$2doi$$a10.3390/jcm14072267
000162580 0248_ $$2sideral$$a145062
000162580 037__ $$aART-2025-145062
000162580 041__ $$aeng
000162580 100__ $$aLopez, Iker
000162580 245__ $$aLong-Term Results of Segmentectomy vs. Lobectomy for c-Stage IA Lung Cancer: A Real-Life Study with a Propensity Score Analysis Based on a National Cohort
000162580 260__ $$c2025
000162580 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162580 5203_ $$aBackground/Objectives: The objective was to compare the results of segmentectomy and lobectomy in the treatment of c-stage IA lung cancer in terms of tumor recurrence and 5-year survival. Methods: An observational study was performed using 3533 patients included in the registry of the Spanish VATS Group (GEVATS) of the Spanish Society of Thoracic Surgery (SECT) between 2016 and 2018. A total of 1004 lobectomies and 83 segmentectomies in c-stage IA were selected. Two comparable groups were selected through 2:1 propensity score matching with patient-, tumor- and surgery-related variables, leaving 166 lobectomies and 83 segmentectomies. Tumor recurrence was analyzed by Fisher’s test and overall, cancer-specific, recurrence-free and disease-free survival by Kaplan-Meier and Log-rank tests. Results: Overall recurrence was 23.7% in both groups, with a predominance of locoregional recurrence in segmentectomy (16.2% vs. 11.2%) and distant recurrence in lobectomy (12.5% vs. 7.5%). There was no difference between the two groups in any of the survival types. Overall survival at 5 years was 73.5% (95% CI: 65.5–82.4%) in the lobectomy group vs. 73.1% (95% CI: 60.1–88.9%) in the segmentectomy group. Conclusions: Anatomic segmentectomy may be a valid option in the treatment of c-stage IA lung cancer since the recurrence and long-term survival outcomes compared to lobectomy are equivalent.
000162580 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000162580 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162580 700__ $$aAguinagalde, Borja
000162580 700__ $$aFerrer-Bonsoms, Juan A.
000162580 700__ $$aSánchez, Laura
000162580 700__ $$aAscanio, Fernando
000162580 700__ $$aSesma, Julio
000162580 700__ $$aRecuero, José Luis
000162580 700__ $$aFernandez-Monge, Arantza
000162580 700__ $$aLizarbe, Jon A.
000162580 700__ $$0(orcid)0000-0003-0249-3104$$aEmbun, Raul$$uUniversidad de Zaragoza
000162580 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía
000162580 773__ $$g14, 7 (2025), 2267 [12 pp.]$$pJ. clin.med.$$tJournal of Clinical Medicine$$x2077-0383
000162580 8564_ $$s1079465$$uhttps://zaguan.unizar.es/record/162580/files/texto_completo.pdf$$yVersión publicada
000162580 8564_ $$s2575259$$uhttps://zaguan.unizar.es/record/162580/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162580 909CO $$ooai:zaguan.unizar.es:162580$$particulos$$pdriver
000162580 951__ $$a2025-10-17-14:21:14
000162580 980__ $$aARTICLE