162583 20260107185710.0 doi 10.1016/j.arbres.2023.03.010 sideral 145066 ART-2023-145066 eng Romero Román, Alejandra Pathological N1/N2 in Clinical Stage I Bronchogenic Carcinoma. Analysis From a Prospective Multicentre Database 2023 Objectives: To determine the incidence of occult N1/N2 nodal metastases and associated risk factors in patients with non-small cell lung cancer no larger than 3 cm and deemed cN0 by CT and PET-CT in a prospective, multicentre national database. Methods: Patients with a NSCLC no larger than 3 cm, deemed cN0 by PET-CT and CT scan, who had undergone at least a lobectomy, were selected from a national multicentre database of 3533 patients who had undergone anatomic lung resection between 2016 and 2018. Clinical and pathological variables of patients with pN0 and patients with pN1/N2 were compared to identify factors associated with the presence of lymph node metastases. Chi2 and the Mann–Whitney U test were used for categorical and numerical variables, respectively. All variables with p < 0.2 in the univariate analysis were included in the multivariate logistic regression analysis. Results: The study included 1205 patients from the cohort. The incidence of occult pN1/N2 disease was 10.70% (95%CI, 9.01–12.58). The multivariable analysis revealed that the degree of differentiation, size, location (central or peripheral) and SUV of the tumour in PET, surgeon experience and number of lymph nodes resected were associated with occult N1/N2 metastases. Conclusions: The incidence of occult N1/N2 in patients with bronchogenic carcinoma with cN0 tumours no larger than 3 cm is no negligible. Data about the degree of differentiation, tumour size in CT scan, maximal uptake of the tumour in PET-CT, location (central or peripheral), number of lymph nodes resected and surgeon seniority is relevant in order to detect patients at risk. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 8.7 2023 RESPIRATORY SYSTEM 9 / 101 = 0.089 2023 Q1 T1 0.464 2023 Pulmonary and Respiratory Medicine 2023 Q3 3.5 2023 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Crowley Carrasco, Silvana Gil Barturen, Mariana Royuela, Ana Obiols, Carme Call, Sergi Recuero, José Luis Royo, Íñigo Embún, Raúl Universidad de Zaragoza (orcid)0000-0003-0249-3104 Gómez de Antonio, David 1013 090 Universidad de Zaragoza Dpto. Cirugía Área Cirugía 59, 6 (2023), 364-369 Arch. bronconeumol. Archivos de Bronconeumologia 0300-2896 335804 http://zaguan.unizar.es/record/162583/files/texto_completo.pdf Versión publicada 2463522 http://zaguan.unizar.es/record/162583/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:162583 articulos driver 2026-01-07-18:55:45 ARTICLE