000162585 001__ 162585 000162585 005__ 20251017144620.0 000162585 0247_ $$2doi$$a10.1016/j.cireng.2023.05.012 000162585 0248_ $$2sideral$$a145071 000162585 037__ $$aART-2023-145071 000162585 041__ $$aeng 000162585 100__ $$aFra-Fernández, Sara 000162585 245__ $$aPostoperative morbidity after anatomical lung resections by VATS vs thoracotomy: Treatment and intention-to-treat analysis of the Spanish Video-Assisted Thoracic Surgery Group 000162585 260__ $$c2023 000162585 5203_ $$aObjectives: In recent years, video-assisted thoracoscopic lung resections (VATS) have been associated with lower morbidity than open surgery. The aim of our study is to compare postoperative morbidity among patients from the national database of the Spanish Group of Video-Assisted Thoracic Surgery (GE-VATS) after open and video-assisted anatomic lung resections using a propensity score analysis. Methods: From December 2016 to March 2018, a total of 3533 patients underwent anatomical lung resection at 33 centers. Pneumonectomies and extended resections were excluded. A propensity score analysis was performed to compare the morbidity of the thoracotomy group (TG) vs the VATS group (VATSG). Treatment and intention-to-treat (ITT) analyses were conducted. Results: In total, 2981 patients were finally included in the study: 1092 (37%) in the TG and 1889 (63%) in the VATSG for the treatment analysis; and 816 (27.4%) in the TG and 2165 patients (72.6%) in the VATSG for the ITT analysis. After propensity score matching, in the treatment analysis, the VATSG was significantly associated with fewer overall complications than the TG OR 0.680 [95%CI 0.616, 0.750]), fewer respiratory (OR 0.571 [0.529, 0.616]) cardiovascular (OR 0.529 [0.478, 0.609]) and surgical (OR 0.875 [0.802, 0.955]) complications, lower readmission rate (OR 0.669 [0.578, 0.775]) and a reduction of hospital length of stay (−1.741 ([−2.073, −1.410]). Intention-to-treat analysis showed only statistically significant differences in overall complications (OR 0.76 [0.54–0.99]) in favor of the VATSG. Conclusion: In this multicenter population, VATS anatomical lung resections have been associated with lower morbidity than those performed by thoracotomy. However, when an intention-to-treat analysis was performed, the benefits of the VATS approach were less prominent. 000162585 540__ $$9info:eu-repo/semantics/closedAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/ 000162585 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000162585 700__ $$aMuñoz-Molina, Gemma María 000162585 700__ $$aCabañero-Sánchez, Alberto 000162585 700__ $$adel Campo-Albendea, Laura 000162585 700__ $$aBolufer-Nadal, Sergio 000162585 700__ $$0(orcid)0000-0003-0249-3104$$aEmbún-Flor, Raúl$$uUniversidad de Zaragoza 000162585 700__ $$aMartínez-Hernández, Néstor J. 000162585 700__ $$aMoreno-Mata, Nicolás 000162585 7102_ $$11013$$2090$$aUniversidad de Zaragoza$$bDpto. Cirugía$$cÁrea Cirugía 000162585 773__ $$g101, 11 (2023), 778-786$$pCir. esp. (Engl. ed.)$$tCirugía Española (English Ed.)$$x2173-5077 000162585 8564_ $$s351545$$uhttps://zaguan.unizar.es/record/162585/files/texto_completo.pdf$$yVersión publicada 000162585 8564_ $$s2144946$$uhttps://zaguan.unizar.es/record/162585/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000162585 909CO $$ooai:zaguan.unizar.es:162585$$particulos$$pdriver 000162585 951__ $$a2025-10-17-14:21:32 000162585 980__ $$aARTICLE