162627 20251017144614.0 doi 10.3390/diseases13080231 sideral 145170 ART-2025-145170 eng Ioannidis, Orestis Optimizing Perioperative Care in Esophageal Surgery: The EUropean PErioperative MEdical Networking (EUPEMEN) Collaborative for Esophagectomy 2025 Access copy available to the general public Unrestricted Background/Objectives: Despite advancements in surgery, esophagectomy remains one of the most challenging and complex gastrointestinal surgical procedures, burdened by significant perioperative morbidity and mortality rates, as well as high financial costs. Recognizing the need for standardized care provided by a multidisciplinary healthcare team, the EUropean PErioperative MEdical Networking (EUPEMEN) initiative developed a dedicated protocol for perioperative care of patients undergoing esophagectomy, aiming to enhance recovery, reduce morbidity, and homogenize care delivery across European healthcare systems. Methods: Developed through a multidisciplinary European collaboration of five partners, the protocol incorporates expert consensus and the latest scientific evidence. It addresses the entire perioperative pathway, from preoperative preparation to hospital discharge and postoperative recovery, emphasizing patient-centered care, risk mitigation, and early functional restoration. Results: The implementation of the EUPEMEN esophagectomy protocol is expected to improve patient outcomes through a day-by-day structured prehabilitation plan, meticulous intraoperative management, and proactive postoperative rehabilitation. The approach promotes reduced postoperative complications, earlier return to oral intake, and shorter hospital stays, while supporting multidisciplinary coordination. Conclusions: The EUPEMEN protocol for esophagectomy provides a comprehensive guideline framework for optimizing perioperative care in esophageal surgery. In addition, it serves as a practical guide for healthcare professionals committed to advancing surgical recovery and standardizing clinical practice across diverse care environments across Europe. info:eu-repo/grantAgreement/EUR/ERASMUS/2020-1-ES01-KA203-082681 info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Anestiadou, Elissavet Koltsida, Angeliki Ramirez, Jose M. Universidad de Zaragoza (orcid)0000-0001-7964-1166 Fabbri, Nicolò Martínez Ubieto, Javier Universidad de Zaragoza (orcid)0000-0003-2462-1904 Feo, Carlo Vittorio Pesce, Antonio Rosetzka, Kristyna Arroyo, Antonio Kocián, Petr Sánchez-Guillén, Luis Pascual Bellosta, Ana Universidad de Zaragoza (orcid)0000-0001-9440-8282 Whitley, Adam Bona Enguita, Alejandro Teresa-Fernandéz, Marta Bitsianis, Stefanos Symeonidis, Savvas 1013 090 Universidad de Zaragoza Dpto. Cirugía Área Cirugía 13, 8 (2025), 231 [31 pp.] Diseases Diseases 2079-9721 4379388 http://zaguan.unizar.es/record/162627/files/texto_completo.pdf Versión publicada 2669791 http://zaguan.unizar.es/record/162627/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:162627 articulos driver 2025-10-17-14:18:42 ARTICLE