000162716 001__ 162716
000162716 005__ 20251017144602.0
000162716 0247_ $$2doi$$a10.3389/fphar.2025.1530139
000162716 0248_ $$2sideral$$a145369
000162716 037__ $$aART-2025-145369
000162716 041__ $$adeu
000162716 100__ $$aBengoa-Urrengoechea, Irantzu
000162716 245__ $$aFactors associated with prescription of modern antidiabetics in newly diagnosed patients with type 2 diabetes. a real-world data study in a Spanish region
000162716 260__ $$c2025
000162716 5060_ $$aAccess copy available to the general public$$fUnrestricted
000162716 5203_ $$aAimTo describe the patterns of first prescription of antidiabetic drugs (AD) in patients with type 2 diabetes (T2D) and analyze the factors associated with the prescription of a modern one.MethodsObservational longitudinal study conducted in the CArdiovascular Risk factors for HEalth Services research (CARhES) cohort. Individuals older than 15, resident in Aragón (Spain), diagnosed with T2D during 2018–2022 were selected and followed-up until 31st December 2022. Secondary use of data from the health system provided sociodemographic, clinical and pharmacological prescription information. We also considered additional variables by Basic Healthcare Area (BHA) of residence. AD were classified into “classical” and “modern” and their differences were described and compared. A multilevel methodology stratified by sex was developed, considering individual characteristics and characteristics of the BHA of residence, to analyze the factors associated to a modern AD.ResultsOur population-based cohort of 22,892 patients were mostly male, native, low-income and living in non-depopulated BHA. People who were younger, with heart failure, ischemic heart disease, chronic renal failure, obesity, with a previous major adverse cardiovascular event, higher socioeconomic level or lived in less deprived and more depopulated areas were more likely to get a modern AD prescription.ConclusionOur analyses showed that prescribing practices vary according to a range of sociodemographic, clinical and geographical characteristics. Knowledge of these factors is essential for implementing and improving equitable and person-centered approaches.
000162716 536__ $$9info:eu-repo/grantAgreement/ES/DGA-GRISSA/B09-23R$$9info:eu-repo/grantAgreement/ES/ISCIII/PI22-01193$$9info:eu-repo/grantAgreement/ES/ISCIII-RICAPPS/RD21-0016-0005
000162716 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000162716 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000162716 700__ $$0(orcid)0000-0001-7293-701X$$aAguilar-Palacio, Isabel$$uUniversidad de Zaragoza
000162716 700__ $$0(orcid)0000-0002-6671-5661$$aRabanaque, María José$$uUniversidad de Zaragoza
000162716 700__ $$aLallana, María Jesús
000162716 700__ $$aGamba Cabezas, Adriana
000162716 700__ $$0(orcid)0000-0002-7194-8275$$aMalo, Sara$$uUniversidad de Zaragoza
000162716 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000162716 773__ $$g16 (2025), [11 pp.]$$pFront. pharmacol.$$tFrontiers in Pharmacology$$x1663-9812
000162716 8564_ $$s1032687$$uhttps://zaguan.unizar.es/record/162716/files/texto_completo.pdf$$yVersión publicada
000162716 8564_ $$s2043204$$uhttps://zaguan.unizar.es/record/162716/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000162716 909CO $$ooai:zaguan.unizar.es:162716$$particulos$$pdriver
000162716 951__ $$a2025-10-17-14:14:24
000162716 980__ $$aARTICLE