000163046 001__ 163046
000163046 005__ 20251009133841.0
000163046 0247_ $$2doi$$a10.1016/j.rineng.2025.107376
000163046 0248_ $$2sideral$$a145544
000163046 037__ $$aART-2025-145544
000163046 041__ $$aeng
000163046 100__ $$0(orcid)0000-0003-4361-6676$$aVelarte, Antonio$$uUniversidad de Zaragoza
000163046 245__ $$aOptical fiber integration in PDMS devices for dynamic tissue deformation
000163046 260__ $$c2025
000163046 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163046 5203_ $$aThis study introduces an advanced optical fiber-based stretchable sensing platform designed for precise biomechanical characterization in tissue engineering applications, specifically tailored for cardiac tissue studies. The system is entirely fabricated from biocompatible polydimethylsiloxane (PDMS) material, and features a thin upper membrane and an internal cavity where controlled pneumatic deformation occurs. Deformation is quantified through changes in optical intensity measured through a strategically aligned optical fiber pair, as membrane stretching disrupts total internal reflection conditions. Finite element modeling using COMSOL is used to optimize device geometry and predict deformation, which is subsequently validated through experimental analyses. A custom-designed electronic system with capacity for real-time signal processing ensures stable and sensitive data acquisition. The experimental results show high levels of linearity and repeatability in a physiologically relevant stretch range, highlighting its potential for biomechanical research applications and dynamic tissue stimulation. Future improvements are directed toward extending the reliable deformation operating range through advances in the optical system.
000163046 536__ $$9info:eu-repo/grantAgreement/ES/DGA/GEPM T23-23$$9info:eu-repo/grantAgreement/ES/DGA/LMP94_21$$9info:eu-repo/grantAgreement/ES/DGA/T39-23R$$9info:eu-repo/grantAgreement/ES/ISCIII/PT23-00167$$9info:eu-repo/grantAgreement/ES/MICINN/PID2022-140556OB-I00$$9info:eu-repo/grantAgreement/ES/MICINN/PID2023-149403NB-I00$$9info:eu-repo/grantAgreement/EUR/MICINN/TED2021-130459B-I00
000163046 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000163046 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000163046 700__ $$0(orcid)0000-0001-9710-0910$$aSannino, Andrea$$uUniversidad de Zaragoza
000163046 700__ $$0(orcid)0000-0003-1403-1505$$aOtin, Aranzazu$$uUniversidad de Zaragoza
000163046 700__ $$aSantamaría, Beatriz
000163046 700__ $$0(orcid)0000-0002-8007-5613$$aArtigas, José Ignacio$$uUniversidad de Zaragoza
000163046 700__ $$0(orcid)0000-0002-1960-407X$$aPueyo, Esther$$uUniversidad de Zaragoza
000163046 7102_ $$15008$$2785$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Tecnología Electrónica
000163046 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac.
000163046 773__ $$g28 (2025), 107376 [10 pp.]$$tResults in Engineering$$x2590-1230
000163046 8564_ $$s2044062$$uhttps://zaguan.unizar.es/record/163046/files/texto_completo.pdf$$yVersión publicada
000163046 8564_ $$s2676332$$uhttps://zaguan.unizar.es/record/163046/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000163046 909CO $$ooai:zaguan.unizar.es:163046$$particulos$$pdriver
000163046 951__ $$a2025-10-09-13:25:56
000163046 980__ $$aARTICLE