000163293 001__ 163293
000163293 005__ 20251024172259.0
000163293 0247_ $$2doi$$a10.1089/mdr.2010.0105
000163293 0248_ $$2sideral$$a67746
000163293 037__ $$aART-2011-67746
000163293 041__ $$aeng
000163293 100__ $$0(orcid)0000-0002-3273-6392$$aPardos de la Gándara, M.
000163293 245__ $$aPrevalence and Characterization of Extended-Spectrum Beta-lactamases-Producing Salmonella enterica Isolates in Saragossa, Spain (2001–2008)
000163293 260__ $$c2011
000163293 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163293 5203_ $$aWe analyzed the prevalence of resistance to extended-spectrum cephalosporins (ESCs) among clinical strains of Salmonella enterica collected by the Laboratory of Clinical Microbiology in the University Clinical Hospital Lozano Blesa in the region of Aragón (Spain), for which very few epidemiological information exists. A total of 2,092 strains of S. enterica were identified in stool samples from patients with gastroenteritis. Five isolates showed an extended-spectrum beta-lactamase (ESBL) phenotype: four isolates of S. enterica serotype Virchow harbored the ESBL-encoding blaCTX-M-9 gene and an isolate of serotype Enteritidis carried a blaCTX-M-1 gene, which, to the best of our knowledge, is described here for the first time in this serotype of S. enterica. The five ESC-resistant isolates were also resistant to spectinomycin, streptomycin, kanamycin, sulfonamides, tetracycline, and trimethoprim as well as to nalidixic acid. The ESBL isolate of serotype Enteritidis, however, remained susceptible to kanamycin and nalidixic acid. A class 1 integron of 1.5 kb was detected for the four serotype Virchow isolates with the gene cassette dfrA16–aadA2. The blaCTX-M-9 gene was carried by an ∼300-kb IncHI2 conjugative plasmid in the case of the S. enterica serotype Virchow isolates. The blaCTX-M-1 gene was carried by an ∼100-kb IncI1-N conjugative plasmid for the serotype Enteritidis ESC-resistant isolate. All the four ESC-resistant strains of S. enterica serotype Virchow clustered together in a XbaI pulsed-field gel electrophoresis, which also revealed a strong similarity between them and some pulsotypes of S. enterica serotype Virchow from France.
000163293 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000163293 590__ $$a2.153$$b2011
000163293 591__ $$aINFECTIOUS DISEASES$$b44 / 70 = 0.629$$c2011$$dQ3$$eT2
000163293 591__ $$aPHARMACOLOGY & PHARMACY$$b130 / 259 = 0.502$$c2011$$dQ3$$eT2
000163293 591__ $$aMICROBIOLOGY$$b65 / 113 = 0.575$$c2011$$dQ3$$eT2
000163293 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000163293 700__ $$0(orcid)0000-0002-9742-1463$$aSeral, C.$$uUniversidad de Zaragoza
000163293 700__ $$0(orcid)0000-0002-2519-701X$$aCastillo, F.J.$$uUniversidad de Zaragoza
000163293 700__ $$0(orcid)0000-0002-7068-0983$$aRubio-Calvo M.C.$$uUniversidad de Zaragoza
000163293 700__ $$aWeill, F.X.
000163293 7102_ $$11008$$2630$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Microbiología
000163293 773__ $$g17, 2 (2011), 207-213$$pMicrob. drug resist.$$tMicrobial Drug Resistance$$x1076-6294
000163293 8564_ $$s783199$$uhttps://zaguan.unizar.es/record/163293/files/texto_completo.pdf$$yPostprint
000163293 8564_ $$s967245$$uhttps://zaguan.unizar.es/record/163293/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000163293 909CO $$ooai:zaguan.unizar.es:163293$$particulos$$pdriver
000163293 951__ $$a2025-10-24-16:56:37
000163293 980__ $$aARTICLE