000163321 001__ 163321
000163321 005__ 20251024172259.0
000163321 0247_ $$2doi$$a10.1016/j.exger.2025.112911
000163321 0248_ $$2sideral$$a145743
000163321 037__ $$aART-2025-145743
000163321 041__ $$aeng
000163321 100__ $$0(orcid)0000-0002-5089-7819$$aSubías-Perié, J.$$uUniversidad de Zaragoza
000163321 245__ $$aCost-effectiveness of a multicomponent training programme for older adults with decreased functional capacity: An economic evaluation
000163321 260__ $$c2025
000163321 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163321 5203_ $$aPurpose: This study aimed to (I) examine the resources required to implement a multicomponent training (MCT) programme, (II) assess its impact on health care utilisation cost, and (III) evaluate its cost-effectiveness in older adults with decreased functional capacity.
Methods: A total of 123 older adults (mean age: 80.3 ± 5.9 years) were allocated into a control (CON, n = 64) or training group (TRAIN, n = 59). The TRAIN group performed a 6-month MCT programme, which included aerobic exercise, resistance training, flexibility and balance components, while the CON group continued with their usual care. Functional capacity, frailty and health-related quality of life (HRQoL) were assessed at three different timepoints using the Short Physical Performance Battery (SPPB), Frailty Phenotype of Fried and the EuroQol-5D (EQ-5D), respectively. Primary outcome measures included the costs of delivering the MCT, health care utilisation, quality-adjusted life-years (QALYs), and the incremental cost effectiveness ratio (ICER). Analyses were conducted from a health system perspective with a 6-month time horizon.
Results: While no significant changes were observed in the CON group, the TRAIN group showed improvements in SPPB (+3.38 ± 1.32), HRQoL (+0.07 ± 0.12), and frailty (−0.64 ± 1.06) (all p < 0.05). The average cost per TRAIN participant was €164. Health care utilisation cost was lower for TRAIN compared to CON (€3091 and €4135, respectively). The ICERs were €115/point increase in SPPB and €407/point reduction in frailty score. The cost per QALY gained by the TRAIN participant relative to the usual care cost was €6274. At a willingness-to-pay threshold of €49,000/QALY (Spanish Health System), the probability of the exercise intervention being cost-effective was 100 %.
Conclusions: The 6-month Exernet-Elder 3.0 training programme demonstrated an ICER of €115 per SPPB point gained, €407 per point of frailty reduction, and €6274 per QALY gained. The intervention was low-cost (€164 per participant) and produced clinically meaningful improvements in functional capacity, HRQoL, and frailty. These findings underscore the importance of integrating a structured, group-based exercise programmes into public health strategies to address the growing socioeconomic and health burden associated with ageing populations.
000163321 536__ $$9info:eu-repo/grantAgreement/ES/DGA-IIU/1-2020$$9info:eu-repo/grantAgreement/ES/MCIU/FPU18-05787$$9info:eu-repo/grantAgreement/ES/MINECO/BES-2017-081402
000163321 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000163321 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000163321 700__ $$0(orcid)0000-0001-6523-5511$$aNavarrete-Villanueva, D.$$uUniversidad de Zaragoza
000163321 700__ $$0(orcid)0000-0003-4789-9618$$aFernández-García, A.I.$$uUniversidad de Zaragoza
000163321 700__ $$0(orcid)0000-0003-0330-5558$$aMoradell, A.$$uUniversidad de Zaragoza
000163321 700__ $$0(orcid)0000-0001-7549-8825$$aAlcalá-Nalvaiz, J.T.$$uUniversidad de Zaragoza
000163321 700__ $$aGroessl, E.J.
000163321 700__ $$aAra, I.
000163321 700__ $$aVila-Maldonado, S.
000163321 700__ $$0(orcid)0000-0002-4054-9132$$aPérez-Gómez, J.
000163321 700__ $$0(orcid)0000-0001-7757-3235$$aGonzalez-Gross, M.
000163321 700__ $$0(orcid)0000-0001-6492-2512$$aGómez-Cabello, A.
000163321 700__ $$0(orcid)0000-0002-4303-4097$$aVicente-Rodríguez, G.$$uUniversidad de Zaragoza
000163321 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, J.A.$$uUniversidad de Zaragoza
000163321 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera.
000163321 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000163321 7102_ $$12008$$2640$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Nutrición Bromatología
000163321 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000163321 773__ $$g211 (2025), 112911 [15 pp.]$$pExp. gerontol.$$tExperimental gerontology$$x0531-5565
000163321 8564_ $$s2072563$$uhttps://zaguan.unizar.es/record/163321/files/texto_completo.pdf$$yVersión publicada
000163321 8564_ $$s2539739$$uhttps://zaguan.unizar.es/record/163321/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000163321 909CO $$ooai:zaguan.unizar.es:163321$$particulos$$pdriver
000163321 951__ $$a2025-10-24-16:57:05
000163321 980__ $$aARTICLE