000163729 001__ 163729
000163729 005__ 20251030150827.0
000163729 0247_ $$2doi$$a10.1016/j.ica.2025.122948
000163729 0248_ $$2sideral$$a145790
000163729 037__ $$aART-2025-145790
000163729 041__ $$aeng
000163729 100__ $$aKordestani, Nazanin
000163729 245__ $$aSynthesis, characterizacion and study of novel heterobimetallic RAPTA-type Ru(II) complexes
000163729 260__ $$c2025
000163729 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163729 5203_ $$aThe new monometallic RAPTA complex [RuCl2(η6-p-cym)(dmPTA-κP)](CF3SO3)2 (1) and novel heterobimetallic complexes [RuCl2(η6-p-cym)-μ-(dmoPTA)-(1κP:2κ2N,N′-M(L)Cl2)] (M = Cu (3); M = Cu, L = DMF (3·3DMF); M = Pd (4)) have been synthesized and characterized (dmPTA = N,N′-dimethyl-1,3,5-triaza-7-phosphaadamantane; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane). The synthesized complexes have been fully characterized by elemental analysis and spectroscopic techniques. The crystal structure of the complexes 2, 3·3DMF and 4 were determined by single-crystal X-ray diffraction. The stability of complexes was studied in water and DMSO at room temperature and 37 °C. The anticancer activity against intestinal Caco-2/TC7 cells was studied.
000163729 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000163729 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000163729 700__ $$aMartinez-Aguilera, Alvaro
000163729 700__ $$0(orcid)0000-0002-6674-7364$$aAbas, Elisa
000163729 700__ $$0(orcid)0000-0002-5306-9365$$aGrasa, Laura$$uUniversidad de Zaragoza
000163729 700__ $$aScalambra, Franco
000163729 700__ $$aRomerosa, Antonio
000163729 7102_ $$11012$$2410$$aUniversidad de Zaragoza$$bDpto. Farmac.Fisiol.y Med.L.F.$$cÁrea Fisiología
000163729 773__ $$g589 (2025), 122948 [9 pp.]$$pInorg. Chim. Acta$$tINORGANICA CHIMICA ACTA$$x0020-1693
000163729 8564_ $$s1921308$$uhttps://zaguan.unizar.es/record/163729/files/texto_completo.pdf$$yVersión publicada
000163729 8564_ $$s2338333$$uhttps://zaguan.unizar.es/record/163729/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000163729 909CO $$ooai:zaguan.unizar.es:163729$$particulos$$pdriver
000163729 951__ $$a2025-10-30-14:39:50
000163729 980__ $$aARTICLE