163729 20251030150827.0 doi 10.1016/j.ica.2025.122948 sideral 145790 ART-2025-145790 eng Kordestani, Nazanin Synthesis, characterizacion and study of novel heterobimetallic RAPTA-type Ru(II) complexes 2025 The new monometallic RAPTA complex [RuCl2(η6-p-cym)(dmPTA-κP)](CF3SO3)2 (1) and novel heterobimetallic complexes [RuCl2(η6-p-cym)-μ-(dmoPTA)-(1κP:2κ2N,N′-M(L)Cl2)] (M = Cu (3); M = Cu, L = DMF (3·3DMF); M = Pd (4)) have been synthesized and characterized (dmPTA = N,N′-dimethyl-1,3,5-triaza-7-phosphaadamantane; dmoPTA = 3,7-dimethyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane). The synthesized complexes have been fully characterized by elemental analysis and spectroscopic techniques. The crystal structure of the complexes 2, 3·3DMF and 4 were determined by single-crystal X-ray diffraction. The stability of complexes was studied in water and DMSO at room temperature and 37 °C. The anticancer activity against intestinal Caco-2/TC7 cells was studied. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc https://creativecommons.org/licenses/by-nc/4.0/deed.es info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Martinez-Aguilera, Alvaro Abas, Elisa (orcid)0000-0002-6674-7364 Grasa, Laura Universidad de Zaragoza (orcid)0000-0002-5306-9365 Scalambra, Franco Romerosa, Antonio 1012 410 Universidad de Zaragoza Dpto. Farmac.Fisiol.y Med.L.F. Área Fisiología 589 (2025), 122948 [9 pp.] Inorg. Chim. Acta INORGANICA CHIMICA ACTA 0020-1693 1921308 http://zaguan.unizar.es/record/163729/files/texto_completo.pdf Versión publicada 2338333 http://zaguan.unizar.es/record/163729/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:163729 articulos driver 2025-10-30-14:39:50 ARTICLE