000163891 001__ 163891
000163891 005__ 20251113160752.0
000163891 0247_ $$2doi$$a10.1016/j.fct.2014.10.029
000163891 0248_ $$2sideral$$a89251
000163891 037__ $$aART-2015-89251
000163891 041__ $$aeng
000163891 100__ $$0(orcid)0000-0003-2638-9221$$aCanellas, E.
000163891 245__ $$aRisk assessment derived from migrants identified in several adhesives commonly used in food contact materials
000163891 260__ $$c2015
000163891 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163891 5203_ $$aAdhesives are used to manufacture multilayer materials, where their components pass through the layers and migrate to the food. Nine different adhesives (acrylic, vinyl and hotmelt) and their migration in 21 laminates for future use as market samples have been evaluated and risk assessment has been carried out. A total of 75 volatiles and non volatile compounds were identified by gas chromatography–mass spectrometry and ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry. Most of the compounds migrated below their specific migration limit (SML), lowest observed adverse effect level (LOAEL), no observed adverse effect level (NOAEL) and values recommended by Cramer. Six compounds classified as high toxicity class III according to Cramer classification, migrated over their SML and exposure values recommended by Cramer, when they were applied in the full area of the packaging. Nevertheless, these adhesives fulfill the threshold in the real application as they are applied in a small area of the packaging.
000163891 536__ $$9info:eu-repo/grantAgreement/ES/DGA/T10
000163891 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000163891 590__ $$a3.584$$b2015
000163891 591__ $$aTOXICOLOGY$$b15 / 90 = 0.167$$c2015$$dQ1$$eT1
000163891 591__ $$aFOOD SCIENCE & TECHNOLOGY$$b12 / 125 = 0.096$$c2015$$dQ1$$eT1
000163891 592__ $$a1.202$$b2015
000163891 593__ $$aFood Science$$c2015$$dQ1
000163891 593__ $$aToxicology$$c2015$$dQ1
000163891 593__ $$aMedicine (miscellaneous)$$c2015$$dQ1
000163891 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000163891 700__ $$0(orcid)0000-0002-8765-4319$$aVera, P.$$uUniversidad de Zaragoza
000163891 700__ $$0(orcid)0000-0003-2685-5739$$aNerín, C.$$uUniversidad de Zaragoza
000163891 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica
000163891 7102_ $$12009$$2X$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cProy. investigación HVA
000163891 773__ $$g75 (2015), 79-87$$pFood chem. toxicol.$$tFOOD AND CHEMICAL TOXICOLOGY$$x0278-6915
000163891 8564_ $$s540826$$uhttps://zaguan.unizar.es/record/163891/files/texto_completo.pdf$$yPostprint
000163891 8564_ $$s1261106$$uhttps://zaguan.unizar.es/record/163891/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000163891 909CO $$ooai:zaguan.unizar.es:163891$$particulos$$pdriver
000163891 951__ $$a2025-11-13-14:57:16
000163891 980__ $$aARTICLE