000163898 001__ 163898 000163898 005__ 20251113160752.0 000163898 0247_ $$2doi$$a10.1007/s00216-013-6881-6 000163898 0248_ $$2sideral$$a83982 000163898 037__ $$aART-2013-83982 000163898 041__ $$aeng 000163898 100__ $$0(orcid)0000-0002-8765-4319$$aVera, Paula$$uUniversidad de Zaragoza 000163898 245__ $$aIdentification of non-volatile compounds and their migration from hot melt adhesives used in food packaging materials characterized by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry 000163898 260__ $$c2013 000163898 5060_ $$aAccess copy available to the general public$$fUnrestricted 000163898 5203_ $$aThe identification of unknown non-volatile migrant compounds from adhesives used in food contact materials is a very challenging task because of the number of possible compounds involved, given that adhesives are complex mixtures of chemicals. The use of ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UPLC-MS/QTOF) is shown to be a successful tool for identifying non-targeted migrant compounds from two hot melt adhesives used in food packaging laminates. Out of the seven migrants identified and quantified, five were amides and one was a compound classified in Class II of the Cramer toxicity. None of the migration values exceeded the recommended Cramer exposure values. 000163898 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 000163898 590__ $$a3.578$$b2013 000163898 591__ $$aCHEMISTRY, ANALYTICAL$$b11 / 75 = 0.147$$c2013$$dQ1$$eT1 000163898 591__ $$aBIOCHEMICAL RESEARCH METHODS$$b21 / 77 = 0.273$$c2013$$dQ2$$eT1 000163898 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000163898 700__ $$0(orcid)0000-0003-2638-9221$$aCanellas, Elena 000163898 700__ $$0(orcid)0000-0003-2685-5739$$aNerín, Cristina$$uUniversidad de Zaragoza 000163898 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDpto. Química Analítica$$cÁrea Química Analítica 000163898 773__ $$g405, 14 (2013), 4747-4754$$pAnal. Bioanal. Chem.$$tAnalytical and Bioanalytical Chemistry$$x1618-2642 000163898 8564_ $$s417367$$uhttps://zaguan.unizar.es/record/163898/files/texto_completo.pdf$$yPostprint 000163898 8564_ $$s1378142$$uhttps://zaguan.unizar.es/record/163898/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000163898 909CO $$ooai:zaguan.unizar.es:163898$$particulos$$pdriver 000163898 951__ $$a2025-11-13-14:57:25 000163898 980__ $$aARTICLE