163898 20251113160752.0 doi 10.1007/s00216-013-6881-6 sideral 83982 ART-2013-83982 eng Vera, Paula Universidad de Zaragoza (orcid)0000-0002-8765-4319 Identification of non-volatile compounds and their migration from hot melt adhesives used in food packaging materials characterized by ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry 2013 The identification of unknown non-volatile migrant compounds from adhesives used in food contact materials is a very challenging task because of the number of possible compounds involved, given that adhesives are complex mixtures of chemicals. The use of ultra-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry (UPLC-MS/QTOF) is shown to be a successful tool for identifying non-targeted migrant compounds from two hot melt adhesives used in food packaging laminates. Out of the seven migrants identified and quantified, five were amides and one was a compound classified in Class II of the Cramer toxicity. None of the migration values exceeded the recommended Cramer exposure values. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 3.578 2013 CHEMISTRY, ANALYTICAL 11 / 75 = 0.147 2013 Q1 T1 BIOCHEMICAL RESEARCH METHODS 21 / 77 = 0.273 2013 Q2 T1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Canellas, Elena (orcid)0000-0003-2638-9221 Nerín, Cristina Universidad de Zaragoza (orcid)0000-0003-2685-5739 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 405, 14 (2013), 4747-4754 Anal. Bioanal. Chem. Analytical and Bioanalytical Chemistry 1618-2642 417367 http://zaguan.unizar.es/record/163898/files/texto_completo.pdf Postprint 1378142 http://zaguan.unizar.es/record/163898/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:163898 articulos driver 2025-11-13-14:57:25 ARTICLE