163919 20251113160752.0 doi 10.1016/j.foodchem.2020.126720 sideral 117717 ART-2020-117717 eng Otoukesh, Mahdiyeh Migration of dihydroxyalkylamines from polypropylene coffee capsules to Tenax® and coffee by salt-assisted liquid–liquid extraction and liquid chromatography–mass spectrometry 2020 Migration of N, N-Bis(2-hydroxyethyl) alkyl(C8–C18)amines from five different polypropylene capsules to Tenax® and coffee powder have been studied. A single step extraction-cleanup procedure using salting out liquid–liquid extraction (SALLE) method followed by ultra-high performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS) was applied. The critical parameters on the SALLE procedure such as extracting solvent, extracting volume, sample pH, salt and its concentration were optimized. The recovery values were in the range of 87.5%–106.5%. The %RSD were lower than 3.7%. The limit of detection was improved from 2.3 ng/g in Tenax® to 0.8 ng/g in coffee. The results indicated that the analyzed compounds have the potential to migrate from the polypropylene capsule containers to the coffee. In most of the cases, the migrated values were higher in Tenax® than in coffee in a range between 1.8 and 61%. One sample did not comply with the specific migration limit established by the European Commission. Access copy available to the general public Unrestricted info:eu-repo/grantAgreement/ES/DGA/T53-17R info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 7.514 2020 CHEMISTRY, APPLIED 7 / 74 = 0.095 2020 Q1 T1 NUTRITION & DIETETICS 6 / 87 = 0.069 2020 Q1 T1 FOOD SCIENCE & TECHNOLOGY 7 / 143 = 0.049 2020 Q1 T1 1.772 2020 Analytical Chemistry 2020 Q1 Medicine (miscellaneous) 2020 Q1 Food Science 2020 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Vera, Paula Universidad de Zaragoza (orcid)0000-0002-8765-4319 Wrona, Magdalena Universidad de Zaragoza (orcid)0000-0003-2052-3012 Nerin, Cristina Universidad de Zaragoza (orcid)0000-0003-2685-5739 Es''haghi, Zarrin 2009 750 Universidad de Zaragoza Dpto. Química Analítica Área Química Analítica 2009 X Universidad de Zaragoza Dpto. Química Analítica Proy. investigación HVA 321 (2020), 126720 [7 pp.] Food chem. Food Chemistry 0308-8146 353724 http://zaguan.unizar.es/record/163919/files/texto_completo.pdf Postprint 2505783 http://zaguan.unizar.es/record/163919/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:163919 articulos driver 2025-11-13-14:57:50 ARTICLE