000163927 001__ 163927
000163927 005__ 20251113160752.0
000163927 0247_ $$2doi$$a10.1039/D5CC04768D
000163927 0248_ $$2sideral$$a145936
000163927 037__ $$aART-2025-145936
000163927 041__ $$aeng
000163927 100__ $$0(orcid)0000-0002-1218-7218$$aFernández-Moreira, Vanesa
000163927 245__ $$aCyclometallated Iridium(III) Complexes: Ligand-Driven Selectivity for Chemotherapy and Photodynamic Therapy
000163927 260__ $$c2025
000163927 5060_ $$aAccess copy available to the general public$$fUnrestricted
000163927 5203_ $$aThis study explores two cyclometallated Ir(III) complex families with distinct therapeutic profiles. Benzothiophene derivatives (1, 2) exhibit potent antiproliferative character in the dark, favoring chemotherapy, while benzothiazole analogs (3 and 4) show high photocytotoxicity, ideal for photodynamic therapy. Photophysical studies and subcellular localization analyses highlight ligand-driven selectivity and the role of organelle targeting in therapeutic outcomes.
000163927 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttps://creativecommons.org/licenses/by-nc/4.0/deed.es
000163927 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000163927 700__ $$aMorales-Pioz, Eva$$uUniversidad de Zaragoza
000163927 700__ $$0(orcid)0000-0001-5201-0874$$aRedrado, Marta
000163927 700__ $$aBenedí Visiedo, Andrea
000163927 700__ $$aAquino, Araceli de
000163927 700__ $$0(orcid)0000-0002-7063-1292$$aGarcía-Orduña, Pilar
000163927 700__ $$aRoyo-Cañas, María
000163927 700__ $$aGodino, Javier
000163927 700__ $$aMarzo, Isabel
000163927 700__ $$aRodriguez, Laura
000163927 700__ $$aGimeno, M. Concepción
000163927 7102_ $$12010$$2760$$aUniversidad de Zaragoza$$bDpto. Química Inorgánica$$cÁrea Química Inorgánica
000163927 773__ $$pChem. commun.$$tChemical Communications$$x1359-7345
000163927 8564_ $$s1365246$$uhttps://zaguan.unizar.es/record/163927/files/texto_completo.pdf$$yPostprint
000163927 8564_ $$s1483856$$uhttps://zaguan.unizar.es/record/163927/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000163927 909CO $$ooai:zaguan.unizar.es:163927$$particulos$$pdriver
000163927 951__ $$a2025-11-13-14:58:00
000163927 980__ $$aARTICLE