doi:10.1016/j.foodchem.2021.131777engCanellas, ElenaVera, PaulaNerin, CristinaDreolin, NicolaGoshawk, JeffThe detection and elucidation of oligomers migrating from biodegradable multilayer teacups using liquid chromatography coupled to ion mobility time-of-flight mass spectrometry and gas chromatography-mass spectrometryART-2022-125750Biodegradable materials are increasingly being used in manufacturing processes due to their environmental benefits. In this work, a study has been performed to assess the migration of compounds from biodegradable multilayer teacups to a tea solution. Liquid chromatography in conjunction with ion-mobility quadrupole time of-flight mass spectrometry has been used for the elucidation of non-volatile compounds. An orthogonal projection to latent structures-discriminant analysis has been carried out to compare the tea after migration against untreated tea used as blank. Headspace solid-phase microextraction coupled to gas chromatography-mass spectrometry has been optimised to analyse the migration of volatile compounds. Eight migrants were identified in the tea, six of which were non-intentionally added oligomers. The degree of migration for hot tea ranged from 0.05 and 4.68 mg/kg, exceeding the specific migration limit. Nevertheless, the migration to cold tea was an order of magnitude lower (between 0.003 and 0.56 mg/kg).2022http://zaguan.unizar.es/record/16401010.1016/j.foodchem.2021.131777http://zaguan.unizar.es/record/164010oai:zaguan.unizar.es:164010info:eu-repo/grantAgreement/ES/DGA-FSE/T53-20Rinfo:eu-repo/grantAgreement/ES/MICINN/RTI2018-097805-B-I00Food Chemistry 374 (2022), 131777 [8 pp.]by-nc-ndhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.esinfo:eu-repo/semantics/openAccess