000164025 001__ 164025
000164025 005__ 20251121161350.0
000164025 0247_ $$2doi$$a10.3390/reports8030133
000164025 0248_ $$2sideral$$a146276
000164025 037__ $$aART-2025-146276
000164025 041__ $$aeng
000164025 100__ $$aMogedano-Cruz, Sara
000164025 245__ $$aPercutaneous Peripheral Nerve Stimulation in Chemotherapy-Induced Neuropathy: A Case Report
000164025 260__ $$c2025
000164025 5060_ $$aAccess copy available to the general public$$fUnrestricted
000164025 5203_ $$aBackground and Clinical Significance: Chemotherapy-induced peripheral neuropathy (CIPN) is a frequent and limiting complication of oncological treatment, particularly in patients receiving oxaliplatin. Its onset can significantly affect the quality of life and compromise the continuity of the antineoplastic therapy. Due to the limited efficacy of available pharmacological therapies, percutaneous electrical nerve stimulation (PENS) has been proposed as a non-invasive alternative for symptom management. Case presentation: We report the case of a 75-year-old woman with colorectal adenocarcinoma who developed CIPN following oxaliplatin administration. She underwent a 12-week course of PENS targeting the median nerve, with weekly sessions conducted without interruption of chemotherapy and without adverse effects. The patient showed progressive improvement in neurosensory symptoms, as measured by the EORTC QLQ-CIPN20 questionnaire. Quantitative sensory testing revealed normalization of thermal and vibratory sensitivity and improved mechanical detection thresholds. The cumulative oxaliplatin dose was maintained throughout treatment. Conclusions: PENS may offer an effective and safe therapeutic option for managing CIPN, enabling symptom control without compromising oncological treatment. This case supports the need for controlled clinical trials to confirm efficacy and establish standardized protocols.
000164025 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000164025 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000164025 700__ $$aRomero-Morales, Carlos
000164025 700__ $$ade la Cueva-Reguera, Mónica
000164025 700__ $$aCampbell, Kristin L.
000164025 700__ $$0(orcid)0000-0002-9201-0120$$aHerrero, Pablo$$uUniversidad de Zaragoza
000164025 7102_ $$11006$$2413$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Fisioterapia
000164025 773__ $$g8, 3 (2025), 133 [10 pp.]$$pReports (MDPI)$$tReports$$x2571-841X
000164025 8564_ $$s1558550$$uhttps://zaguan.unizar.es/record/164025/files/texto_completo.pdf$$yVersión publicada
000164025 8564_ $$s2500317$$uhttps://zaguan.unizar.es/record/164025/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000164025 909CO $$ooai:zaguan.unizar.es:164025$$particulos$$pdriver
000164025 951__ $$a2025-11-21-14:25:00
000164025 980__ $$aARTICLE