000164088 001__ 164088
000164088 005__ 20251121161351.0
000164088 0247_ $$2doi$$a10.3390/jcm14207375
000164088 0248_ $$2sideral$$a146263
000164088 037__ $$aART-2025-146263
000164088 041__ $$aeng
000164088 100__ $$0(orcid)0000-0002-1252-2397$$aLobo, Elena$$uUniversidad de Zaragoza
000164088 245__ $$aDementia Prevalence in the CARhES Cohort: Importance of Socioeconomic Level
000164088 260__ $$c2025
000164088 5060_ $$aAccess copy available to the general public$$fUnrestricted
000164088 5203_ $$aObjectives: Dementia preventive strategies might benefit from a comprehensive approach that considers the interplay of biological and social factors. The aim of this study was to examine the prevalence of dementia by sex and age in a cohort of individuals with cardiovascular risk factors, and to assess how sociodemographic and clinical factors are associated with this disease. Methods: Cross-sectional study was conducted on ≥55-year-old individuals from the CARhES (CArdiovascular Risk factors for HEalth Services research) Spanish cohort. Real-world data on sociodemographic, clinical, and drug information was obtained. Dementia cases were identified by diagnoses and pharmacological treatment. Age- and sex-stratified logistic regression models and sex-stratified CTree analyses were used. Results: The prevalence of dementia among the 323,973 individuals in the cohort was 5.2%, 3.4% in men and 6.6% in women, and it increased with age. In both sex groups, stroke and depression were associated with a higher prevalence of dementia for all the age groups, while sex differences were found in the association of the rest of the sociodemographic and clinical variables with dementia. Being older and with lower socioeconomic status were the most predictive factors of dementia prevalence. Stroke was a stronger indicator in men than in women, while hypertension was nearly twice as significant in women. Conclusions: The prevalence of dementia in people with cardiovascular risk factors was 5.2%, similar to that of the general population. Besides age, having a lower socioeconomic level was the most important indicator of dementia, which may justify more resources and care for these populations.
000164088 536__ $$9info:eu-repo/grantAgreement/ES/DGA-GRISSA/B09-23R$$9info:eu-repo/grantAgreement/ES/ISCIII/PI22-01193
000164088 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000164088 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000164088 700__ $$0(orcid)0000-0002-7194-8275$$aMalo, Sara$$uUniversidad de Zaragoza
000164088 700__ $$0(orcid)0000-0001-7293-701X$$aAguilar-Palacio, Isabel$$uUniversidad de Zaragoza
000164088 700__ $$0(orcid)0000-0002-5064-3763$$aCastel-Feced, Sara$$uUniversidad de Zaragoza
000164088 700__ $$aMaldonado, Lina
000164088 700__ $$0(orcid)0000-0003-2284-7862$$aDe la Cámara, Concepción$$uUniversidad de Zaragoza
000164088 700__ $$0(orcid)0000-0002-6671-5661$$aRabanaque, María José$$uUniversidad de Zaragoza
000164088 7102_ $$12007$$2265$$aUniversidad de Zaragoza$$bDpto. Métodos Estadísticos$$cÁrea Estadís. Investig. Opera.
000164088 7102_ $$11007$$2745$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Psiquiatría
000164088 7102_ $$11011$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Ped.Radio.Sal.Pú.$$cÁrea Medic.Prevent.Salud Públ.
000164088 773__ $$g14, 20 (2025), 7375 [15 pp.]$$pJ. clin.med.$$tJournal of Clinical Medicine$$x2077-0383
000164088 8564_ $$s4469433$$uhttps://zaguan.unizar.es/record/164088/files/texto_completo.pdf$$yVersión publicada
000164088 8564_ $$s2420831$$uhttps://zaguan.unizar.es/record/164088/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000164088 909CO $$ooai:zaguan.unizar.es:164088$$particulos$$pdriver
000164088 951__ $$a2025-11-21-14:26:14
000164088 980__ $$aARTICLE