000164098 001__ 164098
000164098 005__ 20251121161351.0
000164098 0247_ $$2doi$$a10.1016/j.jbiomech.2025.113021
000164098 0248_ $$2sideral$$a146198
000164098 037__ $$aART-2026-146198
000164098 041__ $$aeng
000164098 100__ $$aFamaey, Nele
000164098 245__ $$aCommunity challenge towards consensus on characterization of biological tissue: C4Bio’s first findings
000164098 260__ $$c2026
000164098 5060_ $$aAccess copy available to the general public$$fUnrestricted
000164098 5203_ $$aThis study investigates methodological variability across various expert laboratories worldwide, with regards to characterizing the mechanical properties of biological tissues. Two testing rounds were conducted on the specific use case of uniaxial tensile testing of porcine aorta. In the first round, 24 labs were invited to apply their established methods to assess inter-laboratory variability. This revealed significant methodological diversity and associated variability in the stress–stretch results, underscoring the necessity for a standardized approach.
In the second round, a consensus protocol was collaboratively developed and adopted by 19 labs in an attempt to minimize variability. This involved standardized sample preparation and uniformity in testing protocol, including the use of a common cutting and thickness measurement tool. Despite protocol harmonization, significant variability persisted across labs, which could not be solely attributed to inherent biological differences in tissue samples.
These results illustrate the challenges in unifying testing methods across different research settings, underlining the necessity for further refinement of testing practices. Enhancing consistency in biomechanical experiments is pivotal when comparing results across studies, as well as when using the resulting material properties for in silico simulations in medical research.
000164098 540__ $$9info:eu-repo/semantics/embargoedAccess$$aby-nc-nd$$uhttps://creativecommons.org/licenses/by-nc-nd/4.0/deed.es
000164098 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000164098 700__ $$aFehervary, Heleen
000164098 700__ $$aLafon, Yoann
000164098 700__ $$aAkyildiz, Ali
000164098 700__ $$aDreesen, Silke
000164098 700__ $$aBruyère-Garnier, Karine
000164098 700__ $$aAllain, Jean-Marc
000164098 700__ $$aAlloisio, Marta
000164098 700__ $$aAparici-Gil, Alejandro
000164098 700__ $$aCatalano, Chiara
000164098 700__ $$aChassagne, Fanette
000164098 700__ $$aChokhandre, Snehal
000164098 700__ $$aCrevits, Kimberly
000164098 700__ $$aCrielaard, Hanneke
000164098 700__ $$aCunnane, Eoghan
000164098 700__ $$aCunnane, Connor
000164098 700__ $$aDe Leener, Karen
000164098 700__ $$aDesai, Amisha
000164098 700__ $$aDriessen, Rob
000164098 700__ $$aErdemir, Ahmet
000164098 700__ $$aEskandari, Mona
000164098 700__ $$aEvans, Sam
000164098 700__ $$aGasser, Christian
000164098 700__ $$aGebhardt, Marc
000164098 700__ $$aGlasmacher, Birgit
000164098 700__ $$aHolzapfel, Gerhard A.
000164098 700__ $$aIsasi, Mikel
000164098 700__ $$aJennings, Louise
000164098 700__ $$aKurz, Sascha
000164098 700__ $$aLeal-Marin, Sara
000164098 700__ $$aLecomte, Pauline
000164098 700__ $$aMorch, Annie
000164098 700__ $$aMulvihill, John
000164098 700__ $$aNemavhola, Fulufhelo
000164098 700__ $$aPandelani, Thanyani
000164098 700__ $$aPasta, Salvatore
000164098 700__ $$0(orcid)0000-0002-0664-5024$$aPeña, Estefania$$uUniversidad de Zaragoza
000164098 700__ $$aPierrat, Baptiste
000164098 700__ $$aPloeg, Heidi-Lynn
000164098 700__ $$aPolzer, Stanislav
000164098 700__ $$aRausch, Manuel
000164098 700__ $$aSchwarz, David
000164098 700__ $$aScreen, Hazel
000164098 700__ $$aSherifova, Selda
000164098 700__ $$aSommer, Gerhard
000164098 700__ $$aWang, Shengzhang
000164098 700__ $$aWalsh, Darragh
000164098 700__ $$aYadav, Deepesh
000164098 700__ $$aMarchal, Thierry
000164098 700__ $$aGeris, Liesbet
000164098 7102_ $$15004$$2605$$aUniversidad de Zaragoza$$bDpto. Ingeniería Mecánica$$cÁrea Mec.Med.Cont. y Teor.Est.
000164098 773__ $$g194 (2026), 113021 [15 pp.]$$pJ. biomech.$$tJournal of Biomechanics$$x0021-9290
000164098 8564_ $$s6630575$$uhttps://zaguan.unizar.es/record/164098/files/texto_completo.pdf$$yPostprint$$zinfo:eu-repo/date/embargoEnd/2027-01-01
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000164098 951__ $$a2025-11-21-14:26:28
000164098 980__ $$aARTICLE