164172 20251127172930.0 doi 10.1002/vrc2.70265 sideral 146341 ART-2025-146341 eng Ruiz, Héctor Universidad de Zaragoza (orcid)0000-0002-8474-2831 Severe respiratory distress caused by multicentric small lymphocytic B‐cell lymphoma in a Lacaune sheep 2025 A 6-year-old Lacaune ewe from an experimental dairy flock presented with severe respiratory distress, reduced milk production, and mammary nodules. Clinical examination revealed bilateral inspiratory dyspnoea, mucous nasal discharge, a productive cough, and generalised lymphadenomegaly. Although chronic proliferative rhinitis was initially suspected, anti-inflammatory and antibiotic treatment provided only temporary relief. The ewe's condition subsequently deteriorated, culminating in death. Tumour-like masses were detected and confirmed in the nasal cavity, lungs and lymph nodes. Histopathological and immunohistochemical analyses established a diagnosis of B-cell multicentric lymphoma concurrent with ovine pulmonary adenocarcinoma. This case highlights the importance of including rare neoplastic conditions in the differential diagnosis of respiratory and systemic clinical signs in sheep, and emphasises the diagnostic challenges posed by their resemblance to more common diseases. info:eu-repo/semantics/closedAccess All rights reserved http://www.europeana.eu/rights/rr-f/ info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Ruiz de Arcaute, Marta Universidad de Zaragoza (orcid)0000-0002-7655-2472 Quílez, Pablo Universidad de Zaragoza (orcid)0009-0003-9757-3840 Gómez, Álex Universidad de Zaragoza (orcid)0000-0002-9723-9004 Villanueva-Saz, Sergio Universidad de Zaragoza (orcid)0000-0001-6209-4282 1009 773 Universidad de Zaragoza Dpto. Patología Animal Área Sanidad Animal 1009 617 Universidad de Zaragoza Dpto. Patología Animal Área Medicina y Cirugía Animal (2025), e70265 [6 pp.] Vet. rec. case rep. Veterinary Record Case Reports 2052-6121 5105622 http://zaguan.unizar.es/record/164172/files/texto_completo.pdf Versión publicada 2790436 http://zaguan.unizar.es/record/164172/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:164172 articulos driver 2025-11-27-15:16:25 ARTICLE