LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity

Moscoso, Miriam Fuentes-Valverde, Víctor García, Patricia Vallejo, Juan A. Pérez-Ortega, Jesús Santamarina-Fernández, Rebeca Candela, Ana Oviaño, Marina Arenas, Jesús Bou, Germán LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity

10.3389/fcimb.2025.1664169 2025

2025