000165171 001__ 165171
000165171 005__ 20251219174251.0
000165171 0247_ $$2doi$$a10.3390/ani15223325
000165171 0248_ $$2sideral$$a146989
000165171 037__ $$aART-2025-146989
000165171 041__ $$aeng
000165171 100__ $$ade Almeida, André M.
000165171 245__ $$aEffect of a Reduced-Protein Diet Supplemented with Essential Amino Acids on the Muscle Proteome of Female and Entire Male Finishing Pigs
000165171 260__ $$c2025
000165171 5060_ $$aAccess copy available to the general public$$fUnrestricted
000165171 5203_ $$aCrude protein (CP) decrease coupled to amino acid (AAs) supplementation is interesting for swine nutrition. A proteomics approach unraveled physiological events underlying differences between sexes fed two diets: control and low CP in fast-growing Duroc X (Landrace X Large white) finishing pigs. Sixty animals per sex were distributed in pens (five replicate pens/group), fed ad libitum with two isoenergetic diets (145 vs. 125 g CP/kg with AA supplementation; control and low-CP) for 42 days. Semimembranosus muscle was sampled. Five samples per group were used for Label Free proteomics. Four comparisons were considered: Control Males vs. Control Females; Control Females vs. Low CP females; Control males vs. Low CP males, and Low CP males vs. Low CP females, identifying, respectively, 26, 19, 12, and 11 DAPs (Differentially Accumulated Proteins). Control males had higher abundance of proteins related to cell differentiation and growth compared to females, highlighting continual muscle accretion in the former and lipogenesis onset in the latter. Control females and males had increased DAPs related to tissue growth and differentiation compared to Low CP animals that had increased lipid accretion. Both sexes reacted similarly to the two diets. Low CP diet led to advanced lipogenesis and decreased muscle accretion pathways.
000165171 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttps://creativecommons.org/licenses/by/4.0/deed.es
000165171 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000165171 700__ $$aOsório, Hugo
000165171 700__ $$0(orcid)0000-0002-3005-2675$$aLatorre, María Ángeles$$uUniversidad de Zaragoza
000165171 700__ $$0(orcid)0000-0001-6445-849X$$aÁlvarez-Rodríguez, Javier$$uUniversidad de Zaragoza
000165171 7102_ $$12008$$2700$$aUniversidad de Zaragoza$$bDpto. Produc.Animal Cienc.Ali.$$cÁrea Producción Animal
000165171 773__ $$g15, 22 (2025), 3325 [21]$$pAnimals (Basel)$$tAnimals$$x2076-2615
000165171 8564_ $$s1898009$$uhttps://zaguan.unizar.es/record/165171/files/texto_completo.pdf$$yVersión publicada
000165171 8564_ $$s2615369$$uhttps://zaguan.unizar.es/record/165171/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000165171 909CO $$ooai:zaguan.unizar.es:165171$$particulos$$pdriver
000165171 951__ $$a2025-12-19-14:42:18
000165171 980__ $$aARTICLE