165212 20251219174251.0 doi 10.1016/j.ejmp.2020.12.011 sideral 123325 ART-2021-123325 eng Lozares, S. Universidad de Zaragoza (orcid)0000-0002-1530-5662 In vivo dosimetry in low-voltage IORT breast treatments with XR-RV3 radiochromic film 2021 Purpose: The objectives of the study were to establish a procedure for in vivo film-based dosimetry for intraoperative radiotherapy (IORT), evaluate the typical doses delivered to organs at risk, and verify the dose prescription. Materials and methods: In vivo dose measurements were studied using XR-RV3 radiochromic films in 30 patients with breast cancer undergoing IORT using the Axxent® device (Xoft Inc.). The stability of the radiochromic films in the energy ranges used was verified by taking measurements at different depths. The stability of the scanner response was tested, and 5 different calibration curves were constructed for different beam qualities. Six pieces of film were placed in each of the 30 patients. All the pieces were correctly sterilized and checked to ensure that the process did not affect the outcome. All calibration and dose measurements were analyzed using the Radiochromic.com software application. Results: The doses were measured for 30 patients. The doses in contact with the applicator (prescription zone) were 19.8 ± 0.9 Gy. In the skin areas, the doses were as follows: 1–2 cm from the applicator, 1.86 ± 0.77 Gy; 2–5 cm, 0.73 ± 0.14 Gy; and greater than 5 cm, 0.28 ± 0.17 Gy. The dose delivered to the pectoral muscle (tungsten shielding disc) was 0.51 ± 0.27 Gy. Conclusions: The study demonstrated the viability of XR-RV3 films for in vivo dose measurement in the dose and energy ranges applied in a complex procedure, such as breast IORT. The doses in organs at risk were far below the tolerances for cases such as those studied. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by-nc-nd https://creativecommons.org/licenses/by-nc-nd/4.0/deed.es 3.119 2021 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 74 / 136 = 0.544 2021 Q3 T2 0.747 2021 Biophysics 2021 Q2 Radiology, Nuclear Medicine and Imaging 2021 Q2 Medicine (miscellaneous) 2021 Q2 4.6 2021 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Font, J.A. Universidad de Zaragoza (orcid)0000-0003-4732-7409 Gandía, A. Campos, A. Flamarique, S. Ibáñez, R. Villa, D. Alba, V. Jiménez, S. Hernández, M. Casamayor, C. Universidad de Zaragoza Vicente, I. Universidad de Zaragoza (orcid)0000-0001-8122-4599 Hernando, E. Rubio, P. 1011 770 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Radiol. y Medicina Física 1013 090 Universidad de Zaragoza Dpto. Cirugía Área Cirugía 1013 645 Universidad de Zaragoza Dpto. Cirugía Área Obstetricia y Ginecología 81 (2021), 173-181 Phys. med. PHYSICA MEDICA 1120-1797 3720395 http://zaguan.unizar.es/record/165212/files/texto_completo.pdf Versión publicada 2253467 http://zaguan.unizar.es/record/165212/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165212 articulos driver 2025-12-19-14:43:08 ARTICLE