doi:10.1109/MWSCAS53549.2025.11244449engSannino, AndreaWiens, David-PeterOrtmanns, MauritsArtigas, José I.Otín, AránzazuNon-Linear Modeling and Analysis of Amplifier-Less Potentiostat ArchitecturesART-2025-146770In this article, a previously published amplifier-less potentiostat architecture is further examined. Starting with a linearized model, the impact of the most important parameters is studied taking in account the electrodes-solution electrochemical interface. A detailed model is obtained and thoroughly verified, and recommended operating conditions are given for certain limit load conditions. Then, a more complete non-linear model is developed to take in account the measurement uncertainty introduced by the circuit non-linear components. This non-linear model is compared to a time domain description of the circuit and it is verified that it can predict the non-linear behavior with a precision better than 20%. This result enables the circuit designers to compensate for these effects and ultimately reduce the overall measurement uncertainty.2025http://zaguan.unizar.es/record/16529210.1109/MWSCAS53549.2025.11244449http://zaguan.unizar.es/record/165292oai:zaguan.unizar.es:165292info:eu-repo/grantAgreement/ES/MICINN/PID2022-140556OB-I00info:eu-repo/grantAgreement/ES/UZ-IBERCAJA-CAI/IT14-24Conference proceedings (Midwest Symposium on Circuits and Systems) 68 (2025), 618-622All rights reservedhttp://www.europeana.eu/rights/rr-f/info:eu-repo/semantics/openAccess