165293 20251219174252.0 doi 10.1016/j.brachy.2022.01.006 sideral 146971 ART-2022-146971 eng Lozares-Cordero, Sergio Universidad de Zaragoza (orcid)0000-0002-1530-5662 Feasibility of electronic brachytherapy in cervix cancer–A dosimetric comparison of different brachytherapy techniques 2022 Introducción: This study analyzes cases in which electronic brachytherapy (eBT) led to acceptable treatment plans in cervical cancer. Findings were compared with dosimetry values obtained in 192 Ir-based treatments according to the high-risk clinical target volume (HR-CTV) and the disease stage. Material and methods: We retrospectively analyzed 48 patients with cervical cancer from two centers. The patients were treated with 192 Ir based on MRI. It was possible to use interstitial needles via an Utrecht-type applicator. Dosimetry was simulated using eBT and the parameters D90 and D98 (HR-CTV) and D2cc, D1cc, and D0.1cc (bladder, rectum, and sigmoid colon) were evaluated. The Mann-Whitney U test was used for comparison. The overall cohort of patients was analyzed, as were the sub-cohorts based on stage (FIGO stages I + IIA, IIB and III–IV). Finally, the dosimetry of the eBT plans was evaluated, and the plans obtained were classified as “good”, “acceptable”, or “poor”. Results: Statistically significant differences were found between the eBT and 192 Ir plans for D98 (HR-CTV), D1cc and D0.1cc (bladder), and D1cc and D0.1cc (sigmoid colon). A total of 31 cases (64.6%) were considered good, seven (14.6%) were considered acceptable, and 10 (20.8%) were considered poor. For volumes < 30 cc, all the plans were good or acceptable; for volumes > 30 cc, 54.3% were good, and 71.4% were good or acceptable. By stage, eBT plans for patients with stage IB–IIA disease were good in 100%, whereas those for patients with stage IIB were good in 70.6% and III–IV disease were good in 50%. Conclusions: eBT provides appropriate dosimetry for treatment of cervical cancer in selected cases. Access copy available to the general public Unrestricted info:eu-repo/semantics/openAccess by https://creativecommons.org/licenses/by/4.0/deed.es 1.9 2022 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 100 / 135 = 0.741 2022 Q3 T3 ONCOLOGY 215 / 241 = 0.892 2022 Q4 T3 0.741 2022 Radiology, Nuclear Medicine and Imaging 2022 Q2 Oncology 2022 Q2 3.6 2022 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion González Pérez, Victor Pellejero-Pellejero, Santiago Rodríguez Ruiz, Lucia Guinot Rodríguez, José Luis Villafranca-Iturre, Elena Méndez-Villamón, Agustina Universidad de Zaragoza Gandía Martínez, Almudena Fuentemilla-Urío, Naiara Ruggeri, Ricardo 1011 770 Universidad de Zaragoza Dpto. Microb.Ped.Radio.Sal.Pú. Área Radiol. y Medicina Física 21, 4 (2022), 389-396 Brachytherapy Brachytherapy 1538-4721 667189 http://zaguan.unizar.es/record/165293/files/texto_completo.pdf Versión publicada 2353681 http://zaguan.unizar.es/record/165293/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:165293 articulos driver 2025-12-19-14:44:33 ARTICLE